5-苯基-1H-吡唑-4-羧酸合成路线 （共 10 条）
反应条件
sodium hydroxide; potassium permanganate in water T=20 - 98°C;
参考文献
Lebedev; Lebedeva; Sheludyakov; Kovaleva; Ustinova; Kozhevnikov
Russian Journal of General Chemistry, 2005 , vol. 75, # 5 p. 782 - 789
参考文献
Journal of the American Chemical Society, , vol. 43, p. 1202
反应条件
1: 87 percent / POCl3 / 40 - 80 °C 2: 98 percent / NaOH; KMnO4 / H2O / 20 - 98 °C View Scheme
参考文献
Russian Journal of General Chemistry, , vol. 75, # 5 p. 782 - 789
反应条件
1.1: AcONa / ethanol / 0.75 h / Heating 1.2: ethanol / 1 h / Heating 2.1: 87 percent / POCl3 / 40 - 80 °C 3.1: 98 percent / NaOH; KMnO4 / H2O / 20 - 98 °C View Scheme
参考文献
Russian Journal of General Chemistry, , vol. 75, # 5 p. 782 - 789
参考文献
Chemische Berichte, , vol. 66, p. 1209
参考文献
Journal of the American Chemical Society, , vol. 43, p. 1202
反应条件
in methanol; dichloromethane T=20°C; 0.666667 h;
参考文献
MERCK SHARP and; DOHME CORP.; BURGEY, Christopher, S.; POTTEIGER, Craig, M.
Patent: WO2010/111059 A1, 2010 ;
Location in patent: Page/Page column 54 ;
WO 2010/111059 A1
参考文献
v.Auwers; Ungemach
Chemische Berichte, 1933 , vol. 66, p. 1209
参考文献
Dains; Long
Journal of the American Chemical Society, 1921 , vol. 43, p. 1202
反应条件
sodium hydroxide; hydroxylamine-o-sulphonic acid in water
0.5 h; Ambient temperature; Yield given. Title compound not separated from byproducts;
参考文献
Neunhoeffer, Hans; Clausen, Monika; Voetter, Hans-Dieter; Ohl, Harald; Krueger, Carl; Angermund, K.
Liebigs Annalen der Chemie, 1985 , # 9 p. 1732 - 1751
