1-甲基-9H-芴-9-酮合成路线 （共 38 条）
反应条件
1: biphenyl-2-carboxylic acid With n-butyllithium; potassium tert-butylate in benzene
T=60°C; 1 h;
2: With n-butyllithium in benzene
T=60°C; 2 h;
3: methyl iodide in benzene
T=20°C;
参考文献
Tilly, David; Samanta, Subhendu S.; Castanet, Anne-Sophie; De, Asish; Mortier, Jacques
European Journal of Organic Chemistry, 2006 , # 1 p. 174 - 182
反应条件
1: With oxygen; palladium diacetate; copper(II) bis(trifluoromethanesulfonate) in 1,4-dioxane
T=100°C; 24 h; Molecular sieve;
2: With acetic acid in 1,4-dioxane
参考文献
Sun, Chang-Liang; Liu, Na; Li, Bi-Jie; Yu, Da-Gang; Wang, Yang; Shi, Zhang-Jie
Organic Letters, 2010 , vol. 12, # 1 p. 184 - 187
反应条件
1: With palladium diacetate; copper(II) bis(trifluoromethanesulfonate) in 1,4-dioxane
T=90°C; Molecular sieve;
2: With trifluorormethanesulfonic acid in 1,4-dioxane
参考文献
Sun, Chang-Liang; Liu, Na; Li, Bi-Jie; Yu, Da-Gang; Wang, Yang; Shi, Zhang-Jie
Organic Letters, 2010 , vol. 12, # 1 p. 184 - 187
反应条件
1.1: magnesium / tetrahydrofuran / 2 h / 20 - 85 °C
1.2: 0 - 20 °C / |Inert atmosphere
2.1: pyridinium chlorochromate; triethylamine / dichloromethane / 20 °C
3.1: palladium diacetate; trifluoroacetic acid; potassium carbonate; silver(l) oxide / 24 h / 140 °C / |Schlenk technique; |Inert atmosphere
View Scheme
参考文献
Li, Hu; Zhu, Ru-Yi; Shi, Wen-Juan; He, Ke-Han; Shi, Zhang-Jie
Organic Letters, 2012 , vol. 14, # 18 p. 4850 - 4853,4
反应条件
1: pyridinium chlorochromate; triethylamine / dichloromethane / 20 °C
2: palladium diacetate; trifluoroacetic acid; potassium carbonate; silver(l) oxide / 24 h / 140 °C / |Schlenk technique; |Inert atmosphere
View Scheme
参考文献
Li, Hu; Zhu, Ru-Yi; Shi, Wen-Juan; He, Ke-Han; Shi, Zhang-Jie
Organic Letters, 2012 , vol. 14, # 18 p. 4850 - 4853,4
反应条件
1: benzene; diethyl ether
2: aq.-ethanolic hydrochloric acid
3: aqueous HCl / Diazotization
View Scheme
参考文献
Lothrop; Goodwin
Journal of the American Chemical Society, 1943 , vol. 65, p. 363,365
反应条件
1: C42H62ClO3PPd; potassium carbonate / toluene / 5 h / 60 °C
2: 2,2,2-trimethylacetic acid / dimethylammonium 2,4-dichlorophenoxyacetate; toluene / 10 h / 120 °C
View Scheme
参考文献
Liu, Tao-Ping; Liao, Yuan-Xi; Xing, Chun-Hui; Hu, Qiao-Sheng
Organic Letters, 2011 , vol. 13, # 9 p. 2452 - 2455
反应条件
1: n-butyllithium / tetrahydrofuran / Cooling
2: dipotassium peroxodisulfate; silver(I) acetate / acetonitrile-D3 / 1 h / 130 °C / Microwave irradiation
View Scheme
参考文献
Seo, Sangwon; Slater, Mark; Greaney, Michael F.
Organic Letters, 2012 , vol. 14, # 10 p. 2650 - 2653
反应条件
1: silver carbonate; sodium acetate; dipotassium hydrogenphosphate; palladium diacetate / tert-butyl alcohol / 48 h / 140 °C
2: 1,2-bis-(diphenylphosphino)ethane; trimethylacetic anhydride; [RhCl(η2:η2-cycloocta-1,5-diene)]2; potassium iodide / 20 h / 180 °C / |Inert atmosphere; |Sealed tube
View Scheme
参考文献
Fukuyama, Takahide; Maetani, Shinji; Miyagawa, Kazusa; Ryu, Ilhyong
Organic Letters, 2014 , vol. 16, # 12 p. 3216 - 3219
反应条件
hydrogenchloride
Diazotization;
参考文献
Lothrop; Goodwin
Journal of the American Chemical Society, 1943 , vol. 65, p. 363,365
