反应条件
1: 1.) n-BuLi / 1.) THF, hexane, -10 deg C, 3 h, 2.) THF, hexane, -70 deg C to -40 deg C, 2 h 2: 1.) hydroxylamine hydrochloride, pyridine / 1.) RT, 15 min, 2.) toluene, reflux, 4 h View Scheme
参考文献
Khanna, Ish K.; Weier, Richard M.; Yu, Yi; Xu, Xiang D.; Koszyk, Francis J.; Collins, Paul W.; Koboldt, Carol M.; Veenhuizen, Amy W.; Perkins, William E.; Casier, Jacquelen J.; Masferrer, Jaime L.; Zhang, Yan Y.; Gregory, Susan A.; Seibert, Karen; Isakson, Peter C.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 11 p. 1634 - 1647
