4-(四氢-2H-吡喃-2-基氧基)丁醛合成路线 （共 19 条）
反应条件
oxalyl dichloride; dimethyl sulfoxide; triethylamine in dichloromethane T=-78°C; Swern oxidation; 1 h;
参考文献
Krishna, Palakodety Radha; Srinivas, Ravula
Tetrahedron Asymmetry, 2008 , vol. 19, # 9 p. 1153 - 1160
反应条件
1: pyridinium p-toluenesulfonate / CH2Cl2 / 20 °C 2: pyridinium chlorochromate / CH2Cl2 / 20 °C View Scheme
参考文献
Organic Letters, , vol. 8, # 6 p. 1013 - 1016
反应条件
1.) hydroboration, 2.) modified Moffatt oxidation Yield given;
参考文献
Journal of the American Chemical Society, , vol. 109, # 11 p. 3491 - 3493
反应条件
1: LiAlH4 / diethyl ether 2: oxalyl chloride, DMSO / CH2Cl2 / 0.25 h / -50 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 63, # 2 p. 306 - 313
反应条件
dimethylsulfide; ozone 1.) methanol, -78 deg C, 2.) methanol, from 0 deg C to RT, 3 h; Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 51, # 21 p. 4023 - 4028
反应条件
potassium tert-butylate; lithium diisopropyl amide 1.)-78 deg C,in THF, diluted with ether, 2.) in THF, 1h, at room temperature; Multistep reaction. Title compound not separated from byproducts;
参考文献
Tetrahedron Letters, , vol. 25, # 1 p. 113 - 116
反应条件
1: 53 percent / Al2O3 / CH2Cl2 / 1) 0 deg C, 15 min, 2) r.t., 8 h, 3) 45 deg C, 9 h 2: 64 percent / NaBH4 / ethanol / 2 h / 0 °C View Scheme
参考文献
Ousset, J. B.; Mioskowski, C.; Yang, Y.-L.; Falck, J. R.
Tetrahedron Letters, 1984 , vol. 25, # 51 p. 5903 - 5906
参考文献
Stille, John R.; Grubbs, Robert H.
Journal of Organic Chemistry, 1989 , vol. 54, # 2 p. 434 - 444
反应条件
in tetrahydrofuran
1) 2 h, reflux, 2) 12 h, r.t.;
参考文献
Bestmann, Hans Juergen; Li, Kedong
Chemische Berichte, 1982 , vol. 115, # 2 p. 828 - 831
参考文献
Bestmann; Li
Tetrahedron Letters, 1981 , vol. 22, # 49 p. 4941 - 4944
