(Z)-6-二十一碳烯-11-酮合成路线 （共 124 条）
反应条件
1: 1.25 g / sodium iodide / acetone / 3 h / Heating 2: 90 percent / sodium hydride, DMSO / diethyl ether / 2.5 h / Ambient temperature 3: 100 percent / conc. HCl / CH2Cl2; diethyl ether / 0.17 h / Ambient temperature View Scheme
参考文献
Synthetic Communications, , vol. 13, # 5 p. 379 - 386
反应条件
1: 95 percent / dimethylsulfoxide / 5 h / 100 - 110 °C 2: 2.) conc. HCl / 1.) ether, reflux, 7h, 2.) water, reflux, 2h 3: 5.8 g / hydrogene / Lindlar catalyst / hexane / 20 °C View Scheme
参考文献
Chemistry of Natural Compounds, , vol. 16, # 1 p. 86 - 87
Khimiya Prirodnykh Soedinenii, , vol. 16, # 1 p. 102 - 104
反应条件
1: 2.) conc. HCl / 1.) ether, reflux, 7h, 2.) water, reflux, 2h 2: 5.8 g / hydrogene / Lindlar catalyst / hexane / 20 °C View Scheme
参考文献
Chemistry of Natural Compounds, , vol. 16, # 1 p. 86 - 87
Khimiya Prirodnykh Soedinenii, , vol. 16, # 1 p. 102 - 104
反应条件
1: 82 percent / liquid ammonia / 2 h / -40 °C 2: 95 percent / dimethylsulfoxide / 5 h / 100 - 110 °C 3: 2.) conc. HCl / 1.) ether, reflux, 7h, 2.) water, reflux, 2h 4: 5.8 g / hydrogene / Lindlar catalyst / hexane / 20 °C View Scheme
参考文献
Chemistry of Natural Compounds, , vol. 16, # 1 p. 86 - 87
Khimiya Prirodnykh Soedinenii, , vol. 16, # 1 p. 102 - 104
反应条件
1: 92 percent / H2, quinoline / Lindlar's catalyst / hexane; ethanol 2: 82 percent / Et3N / CH2Cl2 / 3 h 3: 2.) Li2CuCl4 / 1.) THF, 20 min, 2.) THF, a) -10 deg C, 3 h, b) RT, overnight 4: 78 percent / p-toluenesulphonic acid / methanol / 14 h / Ambient temperature 5: 66 percent / PCC / CH2Cl2 6: 69 percent / tetrahydrofuran / 4 h / 0 °C 7: 61 percent / PCC, NaOAc / CH2Cl2 View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 34, # 12 p. 1030 - 1034
反应条件
1: 78 percent / NaH / 18-crown-6 2: 87 percent / osmium tetroxide, sodium periodate / tetrahydrofuran; H2O 3: 65 percent View Scheme
参考文献
Agricultural and Biological Chemistry, , vol. 48, # 8 p. 2151 - 2154
反应条件
1: 1.62 g / pyridine-chromic anhydride complex / CH2Cl2 / 0.25 h / Ambient temperature 2: 1.6 g / hydrogen, pyridine / 10percent Pd-BaSO4 / ethyl acetate View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 1 p. 7 - 10
反应条件
1: 2.2 g / tetrahydrofuran / 3 h / Ambient temperature 2: 1.62 g / pyridine-chromic anhydride complex / CH2Cl2 / 0.25 h / Ambient temperature 3: 1.6 g / hydrogen, pyridine / 10percent Pd-BaSO4 / ethyl acetate View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 1 p. 7 - 10
反应条件
1: aq. 10percent H2SO4 / methanol; H2O / 1 h / Ambient temperature 2: 90 percent / hydrogen peroxide, potassium hydroxide / methanol; H2O / 1 h / 15 °C 3: 7.8 g / tosyl hydrazine / acetic acid; CH2Cl2 / 8 h / Ambient temperature 4: 2.2 g / tetrahydrofuran / 3 h / Ambient temperature 5: 1.62 g / pyridine-chromic anhydride complex / CH2Cl2 / 0.25 h / Ambient temperature 6: 1.6 g / hydrogen, pyridine / 10percent Pd-BaSO4 / ethyl acetate View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 1 p. 7 - 10
反应条件
1: 7.8 g / tosyl hydrazine / acetic acid; CH2Cl2 / 8 h / Ambient temperature 2: 2.2 g / tetrahydrofuran / 3 h / Ambient temperature 3: 1.62 g / pyridine-chromic anhydride complex / CH2Cl2 / 0.25 h / Ambient temperature 4: 1.6 g / hydrogen, pyridine / 10percent Pd-BaSO4 / ethyl acetate View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 1 p. 7 - 10
