(Z)-6-二十一碳烯-11-酮合成路线 （共 124 条）
反应条件
1.1: hexamethylphosphoric acid triamide 1.2: H2 / Lindlar catalyst 1.3: pyridinium chlorochromate 2.1: tetrahydrofuran 3.1: pyridinium chlorochromate / CH2Cl2 View Scheme
参考文献
Bioscience, Biotechnology and Biochemistry, , vol. 69, # 5 p. 957 - 965
反应条件
1: 83 percent / K2CO3 / butan-2-one / 20 h / Heating 2: 84 percent / aq. NaOH / methanol / 48 h / 80 °C View Scheme
参考文献
Bioscience, biotechnology, and biochemistry, , vol. 67, # 7 p. 1559 - 1567
反应条件
1: 71 percent / LiNH2, Fe(NO3)3 / tetrahydrofuran; liquid ammonia 2: 92 percent / H2, quinoline / Lindlar's catalyst / hexane; ethanol 3: 82 percent / Et3N / CH2Cl2 / 3 h 4: 2.) Li2CuCl4 / 1.) THF, 20 min, 2.) THF, a) -10 deg C, 3 h, b) RT, overnight 5: 78 percent / p-toluenesulphonic acid / methanol / 14 h / Ambient temperature 6: 66 percent / PCC / CH2Cl2 7: 69 percent / tetrahydrofuran / 4 h / 0 °C 8: 61 percent / PCC, NaOAc / CH2Cl2 View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 34, # 12 p. 1030 - 1034
反应条件
1: 1.) tert-butyllithium / 1.) ether, hexane, 0 deg C, 2 h, 2.) a) 0 deg C, 0.5 h, b) RT, 0.5 h 2: 100 percent / pyridinium dichromate (PDC) / CH2Cl2 / 41 h / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry, , vol. 50, # 5 p. 719 - 721
反应条件
copper(l) iodide; zinc in ethanol; water 0.75 h; Irradiation;
参考文献
Trehan, I. R.; Singh, Jasvinder; Arora, Ajay K.; Kaur, Jasamrit; Kad, G. L.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1994 , vol. 33, # 5 p. 468 - 469
反应条件
1: 80 percent / toluene; diethyl ether / 2.5 h / 20 - 60 °C 2: 97 percent / pyridine; H2 / Pd/BaSO4 / methanol View Scheme
参考文献
Synlett, , # 6 p. 936 - 938
反应条件
1: pyridine 2: 80 percent / toluene; diethyl ether / 2.5 h / 20 - 60 °C 3: 97 percent / pyridine; H2 / Pd/BaSO4 / methanol View Scheme
参考文献
Synlett, , # 6 p. 936 - 938
反应条件
1: 80 percent 2: 78 percent / NaH / 18-crown-6 3: 87 percent / osmium tetroxide, sodium periodate / tetrahydrofuran; H2O 4: 65 percent View Scheme
参考文献
Agricultural and Biological Chemistry, , vol. 48, # 8 p. 2151 - 2154
反应条件
1: 90 percent / hydrogen peroxide, potassium hydroxide / methanol; H2O / 1 h / 15 °C 2: 7.8 g / tosyl hydrazine / acetic acid; CH2Cl2 / 8 h / Ambient temperature 3: 2.2 g / tetrahydrofuran / 3 h / Ambient temperature 4: 1.62 g / pyridine-chromic anhydride complex / CH2Cl2 / 0.25 h / Ambient temperature 5: 1.6 g / hydrogen, pyridine / 10percent Pd-BaSO4 / ethyl acetate View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 1 p. 7 - 10
反应条件
1: 75 percent / 2-propylmagnesium bromide / (Ph3P)2NiCl2 / tetrahydrofuran; diethyl ether / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 22, # 36 p. 3463 - 3466
