3-羟基-2-氨基苯甲酸合成路线 （共 43 条）
反应条件
enzymatische Umwandlung;
参考文献
Florkin,M.; Mason,H. S.
Comparative Biochemistry, Bd. 4 <New York 1962> S. 306
反应条件
1: 87 percent / HCl gas / 12 h / Heating 2: 67 percent / triethylamine, pyridinium p-toluenesulfonate / xylene / 16 h / Heating View Scheme
参考文献
Goldstein, Steven W.; Dambeck, Paul J.
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 2 p. 335 - 336
反应条件
pyridinium p-toluenesulfonate; triethylamine in xylene 16 h; Heating;
参考文献
Goldstein, Steven W.; Dambeck, Paul J.
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 2 p. 335 - 336
反应条件
1: thionyl chloride / 0 °C / Reflux 2: toluene-4-sulfonic acid; triethylamine; pyridine / xylene / Reflux View Scheme
参考文献
FIBROTECH THERAPEUTICS PTY LTD; WILLIAMS, Spencer John; ZAMMIT, Steven; KELLY, Darren James
Patent: WO2011/47432 A1, 2011 ;
反应条件
2,5-dihydroxy-1,4-benzoquinone in acetic acid T=80°C; 5 h;
参考文献
Hick, Larry A.; Manthey, Michael K.; Truscott, Roger J. W.
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 4 p. 1157 - 1160
反应条件
potassium phosphate; potassium hexacyanoferrate(III) in water 2 h; Ambient temperaturepH 7;
参考文献
Hick, Larry A.; Manthey, Michael K.; Truscott, Roger J. W.
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 4 p. 1157 - 1160
反应条件
3-hydroxyanthranilate 3,4-dioxygenase; oxygen in aq. buffer
参考文献
Huo, Lu; Davis, Ian; Chen, Lirong; Liu, Aimin
Journal of Biological Chemistry, 2013 , vol. 288, # 43 p. 30862 - 30871
参考文献
Journal of the Chemical Society, , p. 980,984
Journal of Biological Chemistry, , vol. 196, p. 185,186
反应条件
hydrogenchloride 12 h; Heating;
参考文献
Journal of Heterocyclic Chemistry, , vol. 27, # 2 p. 335 - 336
反应条件
in methanol; diethyl ether T=0°C; 2 h;
参考文献
Journal of Medicinal Chemistry, , vol. 51, # 23 p. 7344 - 7347
