暂无反应条件数据

1: 89 percent / acetic anhydride / dimethylsulfoxide / 0.25 h / 100 °C 2: 95 percent / aq. sodium hydroxide / 0.08 h View Scheme

boron tribromide in dichloromethane T=-78 - 20°C; 12 h; Inert atmosphere;

sodium ethanolate in ethanol 0.5 h; Ambient temperature;

potassium hydroxide; ethanol

2: KOH, aq. EtOH View Scheme

acetic acid

1: (i) NaNO2, aq. HCl, (ii) /BRN= 1864206/, aq. NaOAc 2: aq. NaOH / methanol / Heating View Scheme

1: 68 percent / triethylamine / tetrahydrofuran / 0.5 h / 25 °C 2: 91 percent / 1,5-diazabicyclo<5.4.0>undec-5-ene / dimethylformamide / 3 h / -15 °C 3: 82 percent / diethyl ether / 0.25 h / 0 °C 4: 90 percent / bromine / acetic acid / 3 h / Ambient temperature 5: 22 percent / 1,5-diazabicyclo<5.4.0>undec-5-ene / benzene 6: 92 percent / boron tribromide / hexane; CH2Cl2 / 0.5 h / Heating 7: 90 percent / sodium ethoxide / ethanol / 0.5 h / Ambient temperature View Scheme

1: 2) dil. aq. hydrochloric acid / 1) diethyl ether, reflux, 3 h, 2) 25 deg C, overnight 2: 68 percent / triethylamine / tetrahydrofuran / 0.5 h / 25 °C 3: 91 percent / 1,5-diazabicyclo<5.4.0>undec-5-ene / dimethylformamide / 3 h / -15 °C 4: 82 percent / diethyl ether / 0.25 h / 0 °C 5: 90 percent / bromine / acetic acid / 3 h / Ambient temperature 6: 22 percent / 1,5-diazabicyclo<5.4.0>undec-5-ene / benzene 7: 92 percent / boron tribromide / hexane; CH2Cl2 / 0.5 h / Heating 8: 90 percent / sodium ethoxide / ethanol / 0.5 h / Ambient temperature View Scheme