N-(2-氨基-4-甲氧基苯基)乙酰胺合成路线 （共 8 条）
反应条件
hydrogen; palladium on activated charcoal in ethanol
参考文献
Shepherd, Thomas; Smith, David M.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 501 - 506
参考文献
DE486079 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 16, p. 2685
反应条件
1: With potassium hydroxide; water in ethanol T=80 - 90°C; 8 - 10 h; 2: With hydrogenchloride in ethanol; water T=10 - 15°C; 3: Alkaline conditions;
参考文献
IPCA LABORATORIES LIMITED
Patent: WO2004/92142 A1, 2004 ;
Location in patent: Page 10 ;
反应条件
in N,N-dimethyl-formamide 89 h; Ambient temperature;
参考文献
Tanaka, Kenjiro; Shimazaki, Michiko; Murakami, Yasuoki
Chemical & Pharmaceutical Bulletin, 1982 , vol. 30, # 8 p. 2714 - 2722
反应条件
1: NaNO2; aqueous HCl 2: aqueous acetic acid View Scheme
参考文献
Fel'dman; Usowskaja
Zhurnal Obshchei Khimii, 1948 , vol. 18, p. 1699,1701
Chem.Abstr., 1949 , p. 2618
反应条件
ethanol; sodium acetate
参考文献
Elderfield et al.
Journal of the American Chemical Society, 1946 , vol. 68, p. 1589
反应条件
sulfuric acid in N,N-dimethyl-formamide
T=120 - 150°C;
参考文献
Tanaka, Kenjiro; Shimazaki, Michiko; Murakami, Yasuoki
Chemical & Pharmaceutical Bulletin, 1982 , vol. 30, # 8 p. 2714 - 2722
反应条件
1: 59.1 percent / dimethylformamide / 89 h / Ambient temperature
2: 63.6 percent / Raney Ni / ethyl acetate / 0.83 h / Heating
View Scheme
参考文献
Tanaka, Kenjiro; Shimazaki, Michiko; Murakami, Yasuoki
Chemical & Pharmaceutical Bulletin, 1982 , vol. 30, # 8 p. 2714 - 2722
