6-甲基烟酸甲酯合成路线

参考文献

European Journal of Organic Chemistry, , # 26 p. 4412 - 4415

参考文献

Tanis, Steven P.; Parker, Timothy T.; Colca, Jerry R.; Fisher, Roberta M.; Kletzein, Rolf F.
Journal of Medicinal Chemistry, 1996 , vol. 39, # 26 p. 5053 - 5063

5470-70-26-甲基烟酸甲酯

101540-79-82-甲基-5-(1-甲基-2-吡咯烷基)吡啶

参考文献

Seeman, Jeffrey I.; Secor, Henry V.; Chavdarian, Charles G.; Sanders, Edward B.; Bassfield, Ronald L.; Whidby, Jerry F.
Journal of Organic Chemistry, 1981 , vol. 46, # 15 p. 3040 - 3048

5470-70-26-甲基烟酸甲酯

146062-48-8羧基吡格列酮(M-V)

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Sohda; Ikeda; Meguro
Chemical and Pharmaceutical Bulletin, 1995 , vol. 43, # 12 p. 2168 - 2172

5470-70-26-甲基烟酸甲酯

146062-44-4羟基匹格列酮

参考文献

Tanis, Steven P.; Parker, Timothy T.; Colca, Jerry R.; Fisher, Roberta M.; Kletzein, Rolf F.
Journal of Medicinal Chemistry, 1996 , vol. 39, # 26 p. 5053 - 5063

5470-70-26-甲基烟酸甲酯

139183-87-2

参考文献

Choong, Ingrid C.; Lew, Willard; Lee, Dennis; Pham, Phuongly; Burdett, Matthew T.; Lam, Joni W.; Wiesmann, Christian; Luong, Tinh N.; Fahr, Bruce; DeLano, Warren L.; McDowell, Robert S.; Allen, Darin A.; Erlanson, Daniel A.; Gordon, Eric M.; O'Brien, Tom
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5470-70-26-甲基烟酸甲酯

106651-81-46-甲基-3-氯甲基吡啶盐酸盐

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ARRAY BIOPHARMA INC.; BOYS, Mark Laurence; DELISLE, Robert Kirk; HICKEN, Erik James; KENNEDY, April L.; MARESKA, David A.; MARMSATER, Fredrik P.; MUNSON, Mark C.; NEWHOUSE, Brad; RAST, Bryson; RIZZI, James P.; RODRIGUEZ, Martha E.; TOPALOV, George T.; ZHAO, Qian
Patent: WO2012/82689 A1, 2012 ;
WO 2012/082689 A1

5470-70-26-甲基烟酸甲酯+

1421227-96-4

1421227-97-5+

221615-75-42-(4-甲磺酰基苯基)-1-(6-甲基吡啶-3-基)-乙酮

参考文献

F.I.S.- Fabbrica Italiana Sintetici S.p.A.; Brasola, Elena; Fontana, Francesco; Stabile, Paolo; Galvagni, Marco
Patent: EP2551265 A1, 2013 ;
Location in patent: Paragraph 0052-0061 ;

5470-70-26-甲基烟酸甲酯+

90536-66-6

221615-75-42-(4-甲磺酰基苯基)-1-(6-甲基吡啶-3-基)-乙酮

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Davies; Marcoux; Corley; Journet; Cai; Palucki; Wu; Larsen; Rossen; Pye; DiMichele; Dormer; Reider
Journal of Organic Chemistry, 2000 , vol. 65, # 25 p. 8415 - 8420

5470-70-26-甲基烟酸甲酯+

1421227-95-3

221615-75-42-(4-甲磺酰基苯基)-1-(6-甲基吡啶-3-基)-乙酮

参考文献

F.I.S.- Fabbrica Italiana Sintetici S.p.A.; Brasola, Elena; Fontana, Francesco; Stabile, Paolo; Galvagni, Marco
Patent: EP2551265 A1, 2013 ;
Location in patent: Paragraph 0067-0089 ;