1,2,3,4-四氢哈尔满-3-羧酸合成路线 （共 7 条）
反应条件
1: With hydrogenchloride in water T=20°C; Pictet-Spengler cyclisation; 12 h; 2: With sodium hydroxide in water pH=8; Heating;
参考文献
Zeng, Yong; Zhang, Yaomou; Weng, Qunfang; Hu, Meiying; Zhong, Guohua
Molecules, 2010 , vol. 15, # 11 p. 7775 - 7791
反应条件
sulfuric acid 1) 60 deg C, 1 h 2) reflux, 1.5 h;
参考文献
Razmilic; Castillo; Lopez
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 3 p. 595 - 596
反应条件
phosphate buffer T=37°C; Maillard reaction; pH=7.0; 672000 h;
参考文献
Bioscience, Biotechnology and Biochemistry, , vol. 69, # 11 p. 2232 - 2235
反应条件
(NH4)2S2O8; silver nitrate in water; acetonitrile T=80°C;
参考文献
Huang, Wenhua; Li, Jingyi; Ou, Lihua
Synthetic Communications, 2007 , vol. 37, # 13 p. 2137 - 2143
反应条件
hydrogenchloride; sodium nitrite in ethanol T=37°C; pH=3; 1 h;
参考文献
Diem, Stefanie; Gutsche, Birgit; Herderich, Markus
Journal of Agricultural and Food Chemistry, 2001 , vol. 49, # 12 p. 5993 - 5998
反应条件
1: HCl 2: sulfur / xylene 3: LiAlH4 / tetrahydrofuran View Scheme
参考文献
Sung; Koike; Nikaido; et al.
Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 5 p. 1872 - 1877
反应条件
1: SOCl2
2: S / xylene; dioxane
View Scheme
参考文献
Razmilic; Castillo; Lopez
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 3 p. 595 - 596
