1-(4-氯苯基)-2-硝基-乙酮合成路线 （共 14 条）
反应条件
hydrogen; sulfided platinum on carbon in hydrogenchloride; ethanol T=50°C; P=760 Torr; 1 h;
参考文献
Tamura, Rui; Oda, Daihei; Kurokawa, Hiroshi
Tetrahedron Letters, 1986 , vol. 27, # 47 p. 5759 - 5762
参考文献
Dann et al.
Zeitschrift fuer Naturforschung, 1952 , vol. 7 b, p. 344,349
反应条件
potassium dichromate; sulfuric acid; water
und Essigsaeure;
参考文献
Dann et al.
Zeitschrift fuer Naturforschung, 1952 , vol. 7 b, p. 344,349
反应条件
tert.-butylhydroperoxide; n-butyllithium in tetrahydrofuran; hexane; toluene
T=-20°C; 1.5 h;
参考文献
Ashwell, Mark A.; Jackson, Richard F. W.
Synthesis, 1988 , # 3 p. 229 - 231
反应条件
(i) NaH, (ii) /BRN= 147356/; Multistep reaction;
参考文献
Baker,D.C.; Putt,S.R.
Synthesis, 1978 , p. 478 - 479
反应条件
TNM in acetonitrile
4 h; Irradiation;
参考文献
Mathew, Lizamma; Varghese, Babu; Sankararaman, S.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1993 , # 12 p. 2399 - 2404
反应条件
1: 2-chloro-5-carboxybenzene With 1,1'-carbonyldiimidazole in tetrahydrofuran
1 h; RefluxInert atmosphere;
2: aci-anion nitromethane sodium salt in tetrahydrofuran; mineral oil
16 h; RefluxInert atmosphere;
参考文献
Lindsay, Vincent N. G.; Lin, Wei; Charette, Andre B.
Journal of the American Chemical Society, 2009 , vol. 131, # 45 p. 16383 - 16385
反应条件
1: sodium acetate / ethanol / 24 h / 20 °C / Inert atmosphere
2: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / ethyl acetate / Reflux; Inert atmosphere
View Scheme
参考文献
Liu, Xiang-Wei; Yan, Yan; Wang, Yong-Qiang; Wang, Chao; Sun, Jian
Chemistry - A European Journal, 2012 , vol. 18, # 30 p. 9204 - 9207
反应条件
1: nitromethane With potassium tert-butylate in dimethyl sulfoxide
T=16°C; 0.166667 h; Inert atmosphere;
2: (1H-1,2,3-benzotriazol-1-yl)(4-chlorophenyl)methanone in dimethyl sulfoxide
T=20°C; 17 h;
参考文献
Takamoto, Mikihiro; Kurouchi, Hiroaki; Otani, Yuko; Ohwada, Tomohiko
Synthesis, 2009 , # 24 art. no. F13909SS, p. 4129 - 4136
反应条件
1.1: tetrahydrofuran / 1 h / Inert atmosphere; Reflux
2.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 20 °C / Inert atmosphere
2.2: 16 h / Inert atmosphere; Reflux
View Scheme
参考文献
Lindsay, Vincent N. G.; Nicolas, Cyril; Charette, Andre B.
Journal of the American Chemical Society, 2011 , vol. 133, # 23 p. 8972 - 8981
