6-甲氧基-喹啉-2-甲腈合成路线 （共 14 条）
反应条件
benzoyl chloride in chloroform T=20°C; 18 h; Heating / reflux;
参考文献
McArthur, Silvia Gatti; Hertel, Cornelia; Nettekoven, Matthias Heinrich; Raab, Susanne; Richter, Hans; Roche, Olivier; Rodriguez-Sarmiento, Rosa Maria; Schuler, Franz
Patent: US2006/84679 A1, 2006 ;
Location in patent: Page/Page column 12 ;
US 20060084679 A1
反应条件
p-toluenesulfonyl chloride in dichloromethane T=25°C; 120 h;
参考文献
Boger; Panek
Journal of Organic Chemistry, 1983 , vol. 48, # 4 p. 621 - 623
反应条件
N,N-di-isopropyl carbamoylchloride in dichloromethane T=20°C;
参考文献
Rodriguez Sarmiento, Rosa Maria; Nettekoven, Matthias H.; Taylor, Sven; Plancher, Jean-Marc; Richter, Hans; Roche, Olivier
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 15 p. 4495 - 4500
反应条件
in dichloromethane; water T=25°C; 120 h;
参考文献
Boger, Dale L.; Brotherton, Christine E.; Panek, James S.; Yohannes, Daniel
Journal of Organic Chemistry, 1984 , vol. 49, # 21 p. 4056 - 4058
反应条件
benzoyl chloride T=20°C; Reflux;
参考文献
Rodriguez Sarmiento, Rosa Maria; Nettekoven, Matthias H.; Taylor, Sven; Plancher, Jean-Marc; Richter, Hans; Roche, Olivier
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 15 p. 4495 - 4500
反应条件
benzoyl chloride in water
参考文献
Kaneko; Fujii; Kawai; et al.
Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 4 p. 1157 - 1171
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in tetrahydrofuran T=0°C; 0.5 h; Yield given;
参考文献
Journal of Organic Chemistry, , vol. 49, # 21 p. 4056 - 4058
反应条件
1: CH2Cl2; H2O / 22 h / 25 °C 2: DBU (1,8-diazabicyclo<5.4.0>undec-7-ene) / tetrahydrofuran / 0.5 h / 0 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 49, # 21 p. 4056 - 4058
参考文献
Zhurnal Obshchei Khimii, , vol. 13, p. 593,600
Chem.Abstr., , p. 705
参考文献
Gazzetta Chimica Italiana, , vol. 83, p. 273,275
