Cis-3,5-二乙酰氧基-1-环戊烯合成路线 （共 14 条）
反应条件
1: porcine pancreatic lipase
2: OsO4, N-methylmorpholine N-oxide
3: TsOH
4: H2 / Pd/C
5: 88 percent / pyridinium dichromate, 4 Angstroem molecular sieves / CH2Cl2
View Scheme
参考文献
Johnson; Penning
Journal of the American Chemical Society, 1988 , vol. 110, # 14 p. 4726 - 4735
反应条件
1: bromine / CCl4 / 3 h / 0 - 5 °C
2: 89 percent / t-BuOK / tetrahydrofuran / -40 - -30 °C
3: 72 percent / K2CO3 / methanol / Ambient temperature
4: POCl3 / CH2Cl2
5: 1.) n-BuLi / 1.) THF, hexane, -78 deg C, 1 h
View Scheme
参考文献
Danikiewicz, Witold; Jaworski, Tadeusz; Kwiatkowski, Stefan
Synthetic Communications, 1983 , vol. 13, # 3 p. 255 - 264
反应条件
1: bromine / CCl4 / 3 h / 0 - 5 °C
2: 89 percent / t-BuOK / tetrahydrofuran / -40 - -30 °C
3: 72 percent / K2CO3 / methanol / Ambient temperature
View Scheme
参考文献
Danikiewicz, Witold; Jaworski, Tadeusz; Kwiatkowski, Stefan
Synthetic Communications, 1983 , vol. 13, # 3 p. 255 - 264
反应条件
(S,S)-DACH-phenyl Trost ligand; BSA; tris(dibenzylideneacetone)dipalladium(0) chloroform complex in dichloromethane
参考文献
Trost, Barry M.; Surivet, Jean-Philippe
Angewandte Chemie - International Edition, 2000 , vol. 39, # 17 p. 3122 - 3124
