(S)-(-)-4-吡啶-1-乙醇合成路线 (共 24 条)
反应条件
potassium tert-butylate; hydrogen; trans-RuCl2[(R)-xylbinap][(R)-daipen] in isopropyl alcohol; tert-butyl alcohol T=25°C; Catalytic hydrogenation; P=6080.41 Torr; 12 h;
参考文献
Ohkuma, Takeshi; Koizumi, Masatoshi; Yoshida, Makoto; Noyori, Ryoji
Organic Letters, 2000 , vol. 2, # 12 p. 1749 - 1751
反应条件
Candida antarctica lipase B; (η5-C5Ph5)Ru(CO)2Cl; potassium tert-butylate; sodium carbonate in tetrahydrofuran; toluene T=50°C; 20 h;
参考文献
Martin-Matute, Belen; Edin, Michaela; Bogar, Krisztian; Kaynak, F. Betuel; Baeckvall, Jan-E.
Journal of the American Chemical Society, 2005 , vol. 127, # 24 p. 8817 - 8825
反应条件
in water T=35°C; 84 h; nonfermenting baker's yeast Saccharomyces cerevisiae;
参考文献
Rasor, Peter; Ruechardt, Christoph
Chemische Berichte, 1989 , vol. 122, p. 1375 - 1376
反应条件
sodium hydroxide in methanol 12 h; Ambient temperature;
参考文献
Takeshita, Mitsuhiro; Terada, Katsuya; Akutsu, Nami; Yoshida, Sachiko; Sato, Takumi
Heterocycles, 1987 , vol. 26, # 12 p. 3051 - 3054
参考文献
Tetrahedron: Asymmetry, , vol. 5, # 7 p. 1363 - 1366
Bioorganic Chemistry, , vol. 27, # 1 p. 3 - 19
反应条件
BES buffer; Lipase from Burkholderia cepacia; calcium chloride in acetonitrile T=30°C; pH=7.2; 2 h; Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 127, # 35 p. 12228 - 12229
反应条件
4 A molecular sieve; Lipase from Burkholderia cepacia in 1,4-dioxane T=30°C; 48 h;
参考文献
Journal of the American Chemical Society, , vol. 127, # 35 p. 12228 - 12229
反应条件
4 A molecular sieve; subtilisin E in 1,4-dioxane T=30°C; 48 h; Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 127, # 35 p. 12228 - 12229
反应条件
Lipase PS-C in di-isopropyl ether T=35°C; 12.3333 h;
参考文献
Itoh, Toshiyuki; Matsushita, Yuichi; Abe, Yoshikazu; Han, Shi-Hui; Wada, Shohei; Hayase, Shuichi; Kawatsura, Motoi; Takai, Shigeomi; Morimoto, Minoru; Hirose, Yoshihiko
Chemistry - A European Journal, 2006 , vol. 12, # 36 p. 9228 - 9237
反应条件
2: K2CO3 / methanol / Ambient temperature View Scheme
参考文献
Journal of the Chemical Society, Chemical Communications, , p. 598 - 600