二甲基-(2-苯基乙炔-苯基)-酰胺合成路线 （共 5 条）
反应条件
1.1: anhydrous iron chloride / dichloromethane / 0.33 h / 25 °C 1.2: air / 24 h / 25 °C 2.1: n-butyllithium / tetrahydrofuran; hexane / 0 °C / |Inert atmosphere 2.2: 0 - 25 °C / |Inert atmosphere View Scheme
参考文献
Speranca, Adriane; Godoi, Benhur; Menezes, Paulo Henrique; Zeni, Gilson
Synlett, 2013 , vol. 24, # 9 art. no. ST-2013-S0135-L, p. 1125 - 1132
反应条件
potassium fluoride; copper(l) iodide; triphenylphosphine; palladium in tetrahydrofuran; water
T=60°C; Sonogashira coupling; 8 h;
参考文献
Wang, Lei; Li, Pinhua
Synthetic Communications, 2003 , vol. 33, # 21 p. 3679 - 3685
反应条件
aluminum oxide; potassium fluoride; triphenylphosphine; copper(l) iodide; palladium
Substitution; Sonogashira reaction; 0.0416667 h; Irradiationin 1000 W microwave oven;
参考文献
Kabalka, George W.; Wang, Lei; Namboodiri, Vasudevan; Pagni, Richard M.
Tetrahedron Letters, 2000 , vol. 41, # 27 p. 5151 - 5154
反应条件
1: 90 percent / KF/Al2O3 / 0.05 h / microwave irradiation (30 percent power)
2: 82 percent / PPh3; CuI; Pd / KF/Al2O3 / 0.04 h / microwave irradiation
View Scheme
参考文献
Kabalka, George W.; Wang, Lei; Pagni, Richard M.
Tetrahedron, 2001 , vol. 57, # 38 p. 8017 - 8028
反应条件
iodine in dichloromethane
T=20°C; 2 h;
参考文献
Yue, Dawei; Larock, Richard C.
Organic Letters, 2004 , vol. 6, # 6 p. 1037 - 1040
Title/Abstract Full Text View citing articles Show Details
Yue, Dawei; Yao, Tuanli; Larock, Richard C.
Journal of Organic Chemistry, 2006 , vol. 71, # 1 p. 62 - 69
