2-氨基-4-甲氧基苯并噻唑合成路线 （共 18 条）
反应条件
1: With bromine in chloroform T=0 - 5°C; Reflux; 2: With ammonia in water
参考文献
Sharma, Pratibha; Kumar, Ashok; Kumari, Prerna; Singh, Jitendra; Kaushik
Medicinal Chemistry Research, 2012 , vol. 21, # 7 p. 1136 - 1148
反应条件
sodium iodide dichloride T=70°C; 4 h;
参考文献
Telvekar, Vikas N.; Bachhav, Harshal M.; Bairwa, Vinod Kumar
Synlett, 2012 , vol. 23, # 15 p. 2219 - 2222
反应条件
bromine; acetic acid T=0 - 20°C;
参考文献
Patel, Navin B.; Agravat, Suresh N.; Shaikh, Faiyazalam M.
Medicinal Chemistry Research, 2011 , vol. 20, # 7 p. 1033 - 1041
反应条件
1: H2O / 4 h / Heating 2: bromine / CHCl3 / 4 h / Heating View Scheme
参考文献
Heterocycles, , vol. 14, # 8 p. 1145 - 1149
反应条件
(i), (ii) Br2; Multistep reaction;
参考文献
Gazzetta Chimica Italiana, , vol. 94, p. 372 - 381
反应条件
1.1: hydrogenchloride / water / 0.5 h / Reflux 1.2: 4 h / 20 °C / Reflux 2.1: bromine / chloroform / 0 - 5 °C / Reflux View Scheme
参考文献
Medicinal Chemistry Research, , vol. 21, # 7 p. 1136 - 1148
反应条件
und Behandeln des Reaktionsprodukts mit wss.Ammoniak;
参考文献
Helvetica Chimica Acta, , vol. 25, p. 515,519
Yakugaku Zasshi, , vol. 60, p. 462,473; dtsch. Ref. S. 184, 189
Chem.Abstr., , p. 452
反应条件
(i) NaNO2, (ii) CuCl; Multistep reaction;
参考文献
Todesco,P.E.; Vivarelli,P.
Gazzetta Chimica Italiana, 1964 , vol. 94, p. 372 - 381
反应条件
1: 1.) diazotating reagent / 2.) THF 2: HBr / acetic acid View Scheme
参考文献
Franke; Frickel; Gries; Lehmann; Lenke; Ohnsorge
Arzneimittel-Forschung, 1980 , vol. 30, # 11 p. 1831 - 1838
反应条件
boron tribromide in dichloromethane T=20°C; 22 h;
参考文献
Jin, Guo Hua; Li, Hua; An, Semi; Ryu, Jae-Ha; Jeon, Raok
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 21 p. 6199 - 6202
