N-(2-氨基-2-甲基丙基)苯胺合成路线 （共 4 条）
反应条件
1: With hydrogenchloride; zinc in methanol; water
T=20°C; 2 h;
2: With ammonia in water
参考文献
KYOWA HAKKO KOGYO CO., LTD.
Patent: EP1354882 A1, 2003 ;
Location in patent: Page/Page column 85 ;
反应条件
[RuCl(N,N-dimethyl-1-[6-(4'-methylphenyl)pyridin-2-yl]methaneamine(-H))(dppb)]; potassium tert-butylate in tetrahydrofuran; toluene
T=110°C; 24 h; Inert atmosphereMolecular sieve;
参考文献
Agrawal, Santosh; Lenormand, Maud; Martin-Matute, Belen
Organic Letters, 2012 , vol. 14, # 6 p. 1456 - 1459
反应条件
1: methanol; water; trimethyl-benzyl-ammonium hydroxide
2: Raney nickel; methanol / 51485.6 Torr / Hydrogenation
View Scheme
参考文献
Johnson
Journal of the American Chemical Society, 1946 , vol. 68, p. 14,16
参考文献
Clapp
Journal of the American Chemical Society, 1948 , vol. 70, p. 184
