1: 4-(phenylmethyl)-1,1'-biphenyl With n-butyllithium in tetrahydrofuran; hexane
T=0 - 20°C; 1 h;
2: carbon dioxide in tetrahydrofuran; hexane
T=20°C; 0.5 h;
3: With hydrogenchloride in tetrahydrofuran; hexane; water
pH=6;
参考文献
METHYLGENE INC.
Patent: WO2008/122115 A1, 2008 ;
Location in patent: Page/Page column 49 ;