1,3-苯并噻唑-2-羧酸3-氧化物合成路线 （共 9 条）
反应条件
1: acetic acid
2: Et3N / acetone / Heating
3: NaOH / Ambient temperature
4: aq. HCl
5: aq. HCl
6: (i) PhLi, Et2O, THF, (ii) /BRN= 1900390/
View Scheme
参考文献
Takahashi,S. et al.
Chemical and Pharmaceutical Bulletin, 1970 , vol. 18, p. 1176 - 1184
反应条件
1: Et3N / acetone / Heating
2: NaOH / Ambient temperature
3: aq. HCl
4: aq. HCl
5: (i) PhLi, Et2O, THF, (ii) /BRN= 1900390/
View Scheme
参考文献
Takahashi,S. et al.
Chemical and Pharmaceutical Bulletin, 1970 , vol. 18, p. 1176 - 1184
反应条件
1: NaNH2, isopentyl nitrite / liquid ammonia
2: acetic acid
3: Et3N / acetone / Heating
4: NaOH / Ambient temperature
5: aq. HCl
6: aq. HCl
7: (i) PhLi, Et2O, THF, (ii) /BRN= 1900390/
View Scheme
参考文献
Takahashi,S. et al.
Chemical and Pharmaceutical Bulletin, 1970 , vol. 18, p. 1176 - 1184
反应条件
1: aq. HCl
2: (i) PhLi, Et2O, THF, (ii) /BRN= 1900390/
View Scheme
参考文献
Takahashi,S. et al.
Chemical and Pharmaceutical Bulletin, 1970 , vol. 18, p. 1176 - 1184
反应条件
1: NaOH / Ambient temperature
2: aq. HCl
3: aq. HCl
4: (i) PhLi, Et2O, THF, (ii) /BRN= 1900390/
View Scheme
参考文献
Takahashi,S. et al.
Chemical and Pharmaceutical Bulletin, 1970 , vol. 18, p. 1176 - 1184
反应条件
1: aq. HCl
2: aq. HCl
3: (i) PhLi, Et2O, THF, (ii) /BRN= 1900390/
View Scheme
参考文献
Takahashi,S. et al.
Chemical and Pharmaceutical Bulletin, 1970 , vol. 18, p. 1176 - 1184
反应条件
1: (i) aq. HCl, aq. NaNO2, (ii) /BRN= 1718733/, (reflux)
2: aq. HCl
3: (i) PhLi, Et2O, THF, (ii) /BRN= 1900390/
View Scheme
参考文献
Takahashi,S. et al.
Chemical and Pharmaceutical Bulletin, 1970 , vol. 18, p. 1176 - 1184
反应条件
1: aq. HCl / Heating
2: (i) PhLi, Et2O, THF, (ii) /BRN= 1900390/
View Scheme
参考文献
Takahashi,S. et al.
Chemical and Pharmaceutical Bulletin, 1970 , vol. 18, p. 1176 - 1184
反应条件
(i) PhLi, Et2O, THF, (ii) /BRN= 1900390/; Multistep reaction;
参考文献
Takahashi,S. et al.
Chemical and Pharmaceutical Bulletin, 1970 , vol. 18, p. 1176 - 1184
