5-硝基-2-甲氧基吡啶合成路线 （共 48 条）
参考文献
Colonna; Dal Monte Casoni
Bollettino Scientifico della Facolta di Chimica Industriale di Bologna, 1944 , vol. 5, p. 32
反应条件
potassium permanganate
T=-7°C; 0.5 h;
参考文献
Szpakiewicz, Barbara; Wozniak, Marian
Advanced Synthesis and Catalysis, 1999 , vol. 341, # 1 p. 75 - 78
反应条件
T=100°C; Hilbert-Johnson reaction; P=6000600 Torr; 96 h;
参考文献
Iida, Hirokazu; Suda, Machiko; Nakajima, Etsuko; Hakamatsuka, Hiroko; Nagashima, Yuka; Joho, Kouta; Amemiya, Kenta; Moromizato, Tatsuya; Matsumoto, Kiyoshi; Murakami, Yasuoki; Hamana, Hiroshi
Heterocycles, 2010 , vol. 81, # 9 p. 2057 - 2062
参考文献
Chem.Fabr.v.Heyden
Patent: DE596821 , 1933 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 21, p. 514
反应条件
1: 97 percent / iron, calcium chloride / aq. ethanol / 2 h / Heating
2: Br2 / acetic acid / 0 - 5 °C
3: HO- / Heating
4: 73 percent / cc. sulfuric acid, sodium sulfite / H2O / 3 h / Heating
View Scheme
参考文献
Okafor; Steenberg; Buckley
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 1 p. 302 - 318
反应条件
1: potassium tert-butylate / tetrahydrofuran; N,N-dimethyl-formamide / 2.33 h / -70 - -60 °C
2: ethanol; water; silver nitrate / 2 h / Reflux; Inert atmosphere
View Scheme
参考文献
Ellis, David
Synthetic Communications, 2011 , vol. 41, # 7 p. 963 - 975
反应条件
1: 97 percent / iron, calcium chloride / aq. ethanol / 2 h / Heating
2: Br2 / acetic acid / 0 - 5 °C
3: HO- / Heating
4: 94 percent / cc. sulfuric acid, sodium sulfite / H2O / 1.75 h / Heating
View Scheme
参考文献
Okafor; Steenberg; Buckley
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 1 p. 302 - 318
反应条件
T=100°C; Hilbert-Johnson reaction; P=6000600 Torr; 72 h;
参考文献
Matsumoto, Kiyoshi; Ikemi, Yukio; Suda, Machiko; Iida, Hirokazu; Hamana, Hiroshi
Heterocycles, 2007 , vol. 72, p. 187 - 190
