5,6-二氨基-1,3-二甲基尿苷水合物合成路线 （共 107 条）
反应条件
sodium dithionite; ammonia in water T=70 - 80°C; 0.25 h;
参考文献
LIFE and BRAIN GMBH; MUeLLER, Christa; ZIMMER, Andreas; LABS, Stefanie; BUCHHOLZ, Stephanie; HINZ, Sonja
Patent: WO2012/76974 A1, 2012 ;
Location in patent: Page/Page column 27; 30 ;
反应条件
1: 95 percent / KNO2; CH3COOH 2: 89 percent / Na2S2O4; NH3 View Scheme
参考文献
Chemistry - A European Journal, , vol. 13, # 13 p. 3724 - 3732
反应条件
sodium dithionite; ammonia
参考文献
Bomkamp, Martin; Siering, Carsten; Landrock, Karin; Stephan, Holger; Froehlich, Roland; Waldvogel, Siegfried R.
Chemistry - A European Journal, 2007 , vol. 13, # 13 p. 3724 - 3732
反应条件
ammonium hydroxide; sodium dithionite 50 deg C then 10 min, reflux;
参考文献
Kuz'menko, V. V.; Kuz'menko, T. A.; Aleksandrov, G. G.; Pozharskii, A. F.; Gulevskaya, A. V.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1987 , vol. 23, # 6 p. 690 - 697
Khimiya Geterotsiklicheskikh Soedinenii, 1987 , vol. 23, # 6 p. 836 - 844
反应条件
1: 86 percent / NaNO2 / H2O / 50 °C 2: Fe, aq. HCl / 0.25 h / 90 °C / pH 5.2 View Scheme
参考文献
Journal of the Indian Chemical Society, , vol. 74, # 8 p. 649 - 651
反应条件
1: 93 percent / water, POCl3 / Heating 2: 98 percent / conc. H2SO4, KNO3 / 1.) 15 min, 7 deg C, 2.) 30 min, 20 deg C 3: 30percent hydrazine / ethanol / 15 min, 20 deg C then 5 min, reflux 4: 60 percent / Na2S2O4, 10percent NH4OH / 50 deg C then 10 min, reflux View Scheme
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 23, # 6 p. 690 - 697
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 23, # 6 p. 836 - 844
反应条件
1: 98 percent / conc. H2SO4, KNO3 / 1.) 15 min, 7 deg C, 2.) 30 min, 20 deg C 2: 30percent hydrazine / ethanol / 15 min, 20 deg C then 5 min, reflux 3: 60 percent / Na2S2O4, 10percent NH4OH / 50 deg C then 10 min, reflux View Scheme
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 23, # 6 p. 690 - 697
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 23, # 6 p. 836 - 844
反应条件
1: 30percent hydrazine / ethanol / 15 min, 20 deg C then 5 min, reflux 2: 60 percent / Na2S2O4, 10percent NH4OH / 50 deg C then 10 min, reflux View Scheme
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 23, # 6 p. 690 - 697
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 23, # 6 p. 836 - 844
反应条件
hydrogenchloride; methanol
参考文献
Chemische Berichte, , vol. 88, p. 1306,1309
反应条件
hydrogenchloride; methanol
参考文献
Chemische Berichte, , vol. 86, p. 325
