2,2-二(羟基甲基)丙烷-1,3-二基二肉豆蔻酸酯合成路线 （共 7 条）
反应条件
hydrogen; palladium on activated charcoal in ethyl acetate
T=20°C; Hydrogenolysis; 24 h;
参考文献
Lizarzaburu, Mike E.; Jones, Ryan M.; Nantz, Michael H.; Kurth, Mark J.
Organic Preparations and Procedures International, 1999 , vol. 31, # 4 p. 440 - 442
反应条件
hydrogen; palladium on activated charcoal in ethyl acetate
Hydrogenation; 24 h;
参考文献
Lizarzaburu, Mike E.; Kurth, Mark J.; Nantz, Michael H.
Tetrahedron Letters, 1999 , vol. 40, # 51 p. 8985 - 8988
反应条件
1: 80 percent / DIBAL-H / hexane; CH2Cl2 / 22 h / 0 - 20 °C
2: 86 percent / Et3N; DMAP / CH2Cl2 / 4 h / 0 - 20 °C
3: 62 percent / H2 / 10 percent Pd/C / ethyl acetate / 24 h
View Scheme
参考文献
Lizarzaburu, Mike E.; Kurth, Mark J.; Nantz, Michael H.
Tetrahedron Letters, 1999 , vol. 40, # 51 p. 8985 - 8988
反应条件
1: 86 percent / Et3N; DMAP / CH2Cl2 / 4 h / 0 - 20 °C
2: 62 percent / H2 / 10 percent Pd/C / ethyl acetate / 24 h
View Scheme
参考文献
Lizarzaburu, Mike E.; Kurth, Mark J.; Nantz, Michael H.
Tetrahedron Letters, 1999 , vol. 40, # 51 p. 8985 - 8988
反应条件
1: 99 percent / TsOH / benzene / 4 h / Heating
2: 92 percent / DIBAL-H / hexane; CH2Cl2 / 12 h / 20 °C
3: 95 percent / Et3N; DMAP / CH2Cl2 / 4 h / 20 °C
4: 96 percent / H2 / 10 percent Pd/C / ethyl acetate / 24 h / 20 °C
View Scheme
参考文献
Lizarzaburu, Mike E.; Jones, Ryan M.; Nantz, Michael H.; Kurth, Mark J.
Organic Preparations and Procedures International, 1999 , vol. 31, # 4 p. 440 - 442
反应条件
1: 95 percent / Et3N; DMAP / CH2Cl2 / 4 h / 20 °C
2: 96 percent / H2 / 10 percent Pd/C / ethyl acetate / 24 h / 20 °C
View Scheme
参考文献
Lizarzaburu, Mike E.; Jones, Ryan M.; Nantz, Michael H.; Kurth, Mark J.
Organic Preparations and Procedures International, 1999 , vol. 31, # 4 p. 440 - 442
反应条件
1: 92 percent / DIBAL-H / hexane; CH2Cl2 / 12 h / 20 °C
2: 95 percent / Et3N; DMAP / CH2Cl2 / 4 h / 20 °C
3: 96 percent / H2 / 10 percent Pd/C / ethyl acetate / 24 h / 20 °C
View Scheme
参考文献
Lizarzaburu, Mike E.; Jones, Ryan M.; Nantz, Michael H.; Kurth, Mark J.
Organic Preparations and Procedures International, 1999 , vol. 31, # 4 p. 440 - 442
