5,6-二甲基-3a,4,7,7a-四氢-2-苯并呋喃-1,3-二酮合成路线 （共 6 条）
反应条件
in 1-methyl-pyrrolidin-2-one T=60°C; Diels-Alder reaction; 0.5 h;
参考文献
Snyder, Daniel A.; Noti, Christian; Seeberger, Peter H.; Schael, Frank; Bieber, Thomas; Rimmel, Guido; Ehrfeld, Wolfgang
Helvetica Chimica Acta, 2005 , vol. 88, # 1 p. 1 - 9
反应条件
1: 68 percent / S8 / various solvent(s) / 2.5 h / 210 - 230 °C 2: 93 percent / formamide / 2 h / 150 °C 3: 40 percent / Sn/HCl / 5 h / Heating View Scheme
参考文献
Hennige, Hans; Kreher, Richard P.; Konrad, Michael; Jelitto, Frank
Chemische Berichte, 1988 , vol. 121, p. 243 - 252
反应条件
sulfuric acid T=100°C; 0.25 h; Overall yield = 73 percentSpectr.;
参考文献
RSC Advances, , vol. 4, # 12 p. 6314 - 6317
反应条件
in acetic acid
2 h; Heating / reflux;
参考文献
Maruishi Pharmaceutical Co., Ltd.
Patent: EP1749817 A1, 2007 ;
Location in patent: Page/Page column 13 ;
反应条件
sulfuric acid
T=100°C; 0.25 h; Overall yield = 73 percentSpectr.;
参考文献
Wang, Fei; Tong, Zhaohui
RSC Advances, 2014 , vol. 4, # 12 p. 6314 - 6317
反应条件
sulfur in various solvent(s)
T=210 - 230°C; 2.5 h;
参考文献
Hennige, Hans; Kreher, Richard P.; Konrad, Michael; Jelitto, Frank
Chemische Berichte, 1988 , vol. 121, p. 243 - 252
