N-[(4-甲基苯基)磺酰基]-3-(2-溴苯基)丙胺合成路线 （共 4 条）
反应条件
triethylamine in dichloromethane
2 h;
参考文献
Wolfe, John P.; Rennels, Roger A.; Buchwald, Stephen L.
Tetrahedron, 1996 , vol. 52, # 21 p. 7525 - 7546
反应条件
1: 99 percent / sodium bicarbonate, tetra-n-butyl ammonium chloride, palladium acetate / dimethylformamide / 48 h / 40 °C
2: 88 percent / NaBH4 / 1,2-dimethoxy-ethane; methanol / 15 h / 70 °C
3: 84 percent / AlCl3, LiAlH4 / diethyl ether / 18 h
4: 65 percent / Et3N / CH2Cl2 / 2 h
View Scheme
参考文献
Wolfe, John P.; Rennels, Roger A.; Buchwald, Stephen L.
Tetrahedron, 1996 , vol. 52, # 21 p. 7525 - 7546
反应条件
1: 88 percent / NaBH4 / 1,2-dimethoxy-ethane; methanol / 15 h / 70 °C
2: 84 percent / AlCl3, LiAlH4 / diethyl ether / 18 h
3: 65 percent / Et3N / CH2Cl2 / 2 h
View Scheme
参考文献
Wolfe, John P.; Rennels, Roger A.; Buchwald, Stephen L.
Tetrahedron, 1996 , vol. 52, # 21 p. 7525 - 7546
反应条件
1: 84 percent / AlCl3, LiAlH4 / diethyl ether / 18 h
2: 65 percent / Et3N / CH2Cl2 / 2 h
View Scheme
参考文献
Wolfe, John P.; Rennels, Roger A.; Buchwald, Stephen L.
Tetrahedron, 1996 , vol. 52, # 21 p. 7525 - 7546
