[3-(2-氯苯基)异噁唑-5-基]甲胺合成路线 （共 5 条）
反应条件
1: sodium hypochlorite; triethylamine / dichloromethane; water / 0 - 20 °C
2: N,N-dimethyl-formamide / 5 h / 20 °C
3: hydrazine hydrate / ethanol / 5 h / Reflux
View Scheme
参考文献
Liu, Yuxiu; Cui, Zhipeng; Liu, Bin; Cai, Baoli; Li, Yonghong; Wang, Qingmin
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 5 p. 2685 - 2689
反应条件
1: hydroxylamine hydrochloride
2: sodium hypochlorite; triethylamine / dichloromethane; water / 0 - 20 °C
3: N,N-dimethyl-formamide / 5 h / 20 °C
4: hydrazine hydrate / ethanol / 5 h / Reflux
View Scheme
参考文献
Liu, Yuxiu; Cui, Zhipeng; Liu, Bin; Cai, Baoli; Li, Yonghong; Wang, Qingmin
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 5 p. 2685 - 2689
反应条件
1: N,N-dimethyl-formamide / 5 h / 20 °C
2: hydrazine hydrate / ethanol / 5 h / Reflux
View Scheme
参考文献
Liu, Yuxiu; Cui, Zhipeng; Liu, Bin; Cai, Baoli; Li, Yonghong; Wang, Qingmin
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 5 p. 2685 - 2689
反应条件
hydrazine hydrate in ethanol
Gabriel reaction; 5 h; Reflux;
参考文献
Liu, Yuxiu; Cui, Zhipeng; Liu, Bin; Cai, Baoli; Li, Yonghong; Wang, Qingmin
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 5 p. 2685 - 2689
反应条件
1: triethylamine / dichloromethane / 11 h / 0 - 20 °C
2: sodium azide / N,N-dimethyl-formamide / 8 h / 55 °C
3: water; ammonium chloride; zinc / ethanol / 0.5 h / Reflux
View Scheme
参考文献
Zhang, Datong; Jia, Jiong; Meng, Lijuan; Xu, Weiren; Tang, Lida; Wang, Jianwu
Archives of Pharmacal Research, 2010 , vol. 33, # 6 p. 831 - 842
