(7Z,9e)-7,9-乙酸十二二烯酯合成路线 （共 87 条）
反应条件
1.1: 9-BBN / tetrahydrofuran / 2 h / 10 °C
1.2: 0.14 g / aq. NaOH; H2O2 / tetrahydrofuran / 2 h / 25 °C
2.1: 1.63 g / pyridine / 24 h / 20 °C
View Scheme
参考文献
Kukovinets; Kasradze; Chernukha; Odinokov; Galin; Abdullin; Fedorov; Tolstikov
Russian Journal of Organic Chemistry, 2000 , vol. 36, # 2 p. 211 - 213
反应条件
1: NiCl2(dppe) / diethyl ether; tetrahydrofuran / 8 h / Ambient temperature
2: p-toluenesulphonic acid / methanol; H2O / 3 h / 0 °C
3: pyridine
View Scheme
参考文献
Fiandanese, V.; Marchese, G.; Naso, F.; Ronzini, L.; Rotunno, D.
Tetrahedron Letters, 1989 , vol. 30, # 2 p. 243 - 246
反应条件
1: NiCl2(dppe) / diethyl ether; tetrahydrofuran / 8 h / Ambient temperature
2: p-toluenesulphonic acid / methanol; H2O / 3 h / 0 °C
3: pyridine
View Scheme
参考文献
Fiandanese, V.; Marchese, G.; Naso, F.; Ronzini, L.; Rotunno, D.
Tetrahedron Letters, 1989 , vol. 30, # 2 p. 243 - 246
反应条件
1: Na / tetrahydrofuran
2: m-chloroperoxybenzoic acid, Na2HPO4 / CH2Cl2 / Ambient temperature
4: 1) BF3*Et2O; 2) FeCl3 / 1) Et2O
View Scheme
参考文献
Alexakis, A.; Jachiet, D.
Tetrahedron, 1989 , vol. 45, # 2 p. 381 - 390
反应条件
1: m-chloroperoxybenzoic acid, Na2HPO4 / CH2Cl2 / Ambient temperature
3: 1) BF3*Et2O; 2) FeCl3 / 1) Et2O
View Scheme
参考文献
Alexakis, A.; Jachiet, D.
Tetrahedron, 1989 , vol. 45, # 2 p. 381 - 390
反应条件
1: Et3N / CH2Cl2
3: 62 percent / pyridine
View Scheme
参考文献
Cassani, G.; Massardo, P.; Piccardi, P.
Tetrahedron Letters, 1983 , vol. 24, # 24 p. 2513 - 2516
反应条件
1: 1.) iBu2AlH, 2.) I2 / 1.) hexane 2.) THF
2: 89 percent / FeCl3 / diethyl ether
3: 92 percent / 3percent Pd(PPh3)4
View Scheme
参考文献
Alexakis, A.; Duffault, J. M.
Tetrahedron Letters, 1988 , vol. 29, # 48 p. 6243 - 6246
反应条件
1: 89 percent / FeCl3 / diethyl ether
2: 92 percent / 3percent Pd(PPh3)4
View Scheme
参考文献
Alexakis, A.; Duffault, J. M.
Tetrahedron Letters, 1988 , vol. 29, # 48 p. 6243 - 6246
反应条件
1: Li2CuCl4 / tetrahydrofuran / 1 h / -5 °C
2: CCl3CO2H / tetrahydrofuran; H2O / 1 h / 60 °C
3: Et3N / CH2Cl2
4: (i) bis-(1,2-dimethyl-propyl)-borane, THF, (ii) AcOH, (iii) CCl3CO2H, MeOH
5: (acetylation)
View Scheme
参考文献
Labovitz,J.N. et al.
Tetrahedron Letters, 1975 , p. 4209 - 4212
反应条件
1: CCl3CO2H / tetrahydrofuran; H2O / 1 h / 60 °C
2: Et3N / CH2Cl2
3: (i) bis-(1,2-dimethyl-propyl)-borane, THF, (ii) AcOH, (iii) CCl3CO2H, MeOH
4: (acetylation)
View Scheme
参考文献
Labovitz,J.N. et al.
Tetrahedron Letters, 1975 , p. 4209 - 4212
