(7Z,9e)-7,9-乙酸十二二烯酯合成路线 （共 87 条）
参考文献
Cassani, G.; Massardo, P.; Piccardi, P.
Tetrahedron Letters, 1983 , vol. 24, # 24 p. 2513 - 2516
反应条件
diisoamyl borane in tetrahydrofuran
T=0°C; 4 h;
参考文献
Descoins,C. et al.
Bulletin de la Societe Chimique de France, 1977 , p. 941 - 946
反应条件
1: 1.02 g / AcOH / 1 h / 0 °C
2: 1.) (Ph3P)4Pd, 2.) copper iodide / 1.) C6H6, 40 min, 2.) 48 h, room temperature
3: diisoamylborane / 89 h
View Scheme
参考文献
Descoins, C.; Lettere, M.; Linsrumelle, G.; Michelot, D.; Ratovelomanana, V.
Synthetic Communications, 1984 , vol. 14, # 8 p. 761 - 774
反应条件
1: 1.) BuLi / 1.) THF
2: methanol
3: NaBH4 / H2O; CCl4
4: 2.) KOH / 1.) CH3OH 2.) 10N KOH
5: TsOH / tetrahydrofuran
6: 88 percent / ethanol
7: Li2CuCl4 / tetrahydrofuran / -25 - 0 °C
8: TsOH / methanol
9: pyridine
View Scheme
参考文献
Dressaire; Langlois
Tetrahedron Letters, 1980 , vol. 21, # 1 p. 67 - 70
反应条件
1: 1.) BuLi / 1.) THF
2: methanol
3: NaBH4 / H2O; CCl4
4: 2.) KOH / 1.) CH3OH 2.) 10N KOH
5: TsOH / tetrahydrofuran
6: 88 percent / ethanol
7: Li2CuCl4 / tetrahydrofuran / -25 - 0 °C
8: TsOH / methanol
9: pyridine
View Scheme
参考文献
Dressaire; Langlois
Tetrahedron Letters, 1980 , vol. 21, # 1 p. 67 - 70
反应条件
1: TsOH / tetrahydrofuran
2: 88 percent / ethanol
3: Li2CuCl4 / tetrahydrofuran / -25 - 0 °C
4: TsOH / methanol
5: pyridine
View Scheme
参考文献
Dressaire; Langlois
Tetrahedron Letters, 1980 , vol. 21, # 1 p. 67 - 70
反应条件
1: 2.) KOH / 1.) CH3OH 2.) 10N KOH
2: TsOH / tetrahydrofuran
3: 88 percent / ethanol
4: Li2CuCl4 / tetrahydrofuran / -25 - 0 °C
5: TsOH / methanol
6: pyridine
View Scheme
参考文献
Dressaire; Langlois
Tetrahedron Letters, 1980 , vol. 21, # 1 p. 67 - 70
反应条件
1: methanol
2: NaBH4 / H2O; CCl4
3: 2.) KOH / 1.) CH3OH 2.) 10N KOH
4: TsOH / tetrahydrofuran
5: 88 percent / ethanol
6: Li2CuCl4 / tetrahydrofuran / -25 - 0 °C
7: TsOH / methanol
8: pyridine
View Scheme
参考文献
Dressaire; Langlois
Tetrahedron Letters, 1980 , vol. 21, # 1 p. 67 - 70
反应条件
1: Li2CuCl4 / tetrahydrofuran / -25 - 0 °C
2: TsOH / methanol
3: pyridine
View Scheme
参考文献
Dressaire; Langlois
Tetrahedron Letters, 1980 , vol. 21, # 1 p. 67 - 70
反应条件
1: Et3N / CH2Cl2
2: (i) bis-(1,2-dimethyl-propyl)-borane, THF, (ii) AcOH, (iii) CCl3CO2H, MeOH
3: (acetylation)
View Scheme
参考文献
Labovitz,J.N. et al.
Tetrahedron Letters, 1975 , p. 4209 - 4212
