2,4-二氯-6-甲基嘧啶合成路线

Thalji, Reema K.; McAtee, Jeff J.; Belyanskaya, Svetlana; Brandt, Martin; Brown, Gregory D.; Costell, Melissa H.; Ding, Yun; Dodson, Jason W.; Eisennagel, Steve H.; Fries, Rusty E.; Gross, Jeffrey W.; Harpel, Mark R.; Holt, Dennis A.; Israel, David I.; Jolivette, Larry J.; Krosky, Daniel; Li, Hu; Lu, Quinn; Mandichak, Tracy; Roethke, Theresa; Schnackenberg, Christine G.; Schwartz, Benjamin; Shewchuk, Lisa M.; Xie, Wensheng; Behm, David J.; Douglas, Stephen A.; Shaw, Ami L.; Marino Jr., Joseph P.
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 12 p. 3584 - 3588

5424-21-52,4-二氯-6-甲基嘧啶

68121-32-42-(嘧啶-4-基)乙醇

参考文献

Overberger; Kogon
Journal of the American Chemical Society, 1954 , vol. 76, p. 1879,1882

5424-21-52,4-二氯-6-甲基嘧啶+

124-40-3二甲胺

535-89-7

参考文献

Semple, Graeme; Tran, Thuy-Anh; Kramer, Bryan; Hsu, Debbie; Han, Sangdon; Choi, Juyi; Vallar, Pureza; Casper, Martin D.; Zou, Ning; Hauser, Erin K.; Thomsen, William; Whelan, Kevin; Sengupta, Dipanjan; Morgan, Michael; Sekiguchi, Yoshinori; Kanuma, Kosuke; Chaki, Shigeyuki; Grottick, Andrew J.
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 21 p. 6166 - 6171

5424-21-52,4-二氯-6-甲基嘧啶+

124-40-3二甲胺

535-89-7+

5734-62-3

参考文献

TAISHO PHARMACEUTICAL CO., LTD.; Arena Pharmaceuticals, Inc
Patent: WO2005/95357 A2, 2005 ;
Location in patent: Page/Page column 137; 138 ;
WO 2005/095357 A2

5424-21-52,4-二氯-6-甲基嘧啶+

4637-24-5N,N-二甲基甲酰胺二甲基缩醛

535-89-7+

5734-62-3

参考文献

Journal of Heterocyclic Chemistry, , vol. 33, # 2 p. 465 - 474