1-异氰酸-3,5-二甲氧基苯酯合成路线 （共 28 条）
反应条件
1: Et3N; diphenylphosphorazidate / benzene / 0.67 h 2: acetonitrile / 1 h / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 40, # 38 p. 6891 - 6894
反应条件
N-ethyl-N,N-diisopropylamine; 4-nitrophenylsulfonyl chloride in tetrahydrofuran T=0°C; Lossen Rearrangement; 2 h; Inert atmosphere;
参考文献
Organic Letters, , vol. 15, # 3 p. 602 - 605
反应条件
hydrogenchloride; sodium nitrite in water
参考文献
Occelli; Fontanella
Farmaco, Edizione Scientifica, 1984 , vol. 39, # 4 p. 322 - 335
反应条件
in toluene 2.5 h; Heating;
参考文献
Durrani, Aziz A.; Tyman, John H. P.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1658 - 1666
反应条件
1: hydroxylamine / acetonitrile; water / 14 h / 23 °C 2: 4-nitrophenylsulfonyl chloride; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 2 h / 0 °C / |Inert atmosphere View Scheme
参考文献
Organic Letters, , vol. 15, # 3 p. 602 - 605
反应条件
1: 78 percent / hydrazine hydrate / 2 h / Heating 2: 63 percent / sodium nitrite, hydrochloric acid (2M), acetic acid (glacial) / H2O / 1 h / -10 °C 3: 93 percent / toluene / 2.5 h / Heating View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1658 - 1666
反应条件
1: 84 percent / sodium hydroxide / heating 2: 88 percent / conc. sulphuric acid / 16 h / Heating 3: 78 percent / hydrazine hydrate / 2 h / Heating 4: 63 percent / sodium nitrite, hydrochloric acid (2M), acetic acid (glacial) / H2O / 1 h / -10 °C 5: 93 percent / toluene / 2.5 h / Heating View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1658 - 1666
反应条件
1: potassium carbonate / acetonitrile / 20 °C 2: sodium hydroxide / 1,4-dioxane / 5 h / 20 °C 3: triethylamine; diphenyl phosphoryl azide / 80 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 24 p. 7451 - 7455
反应条件
1: sodium hydroxide / 1,4-dioxane / 5 h / 20 °C 2: triethylamine; diphenyl phosphoryl azide / 80 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 24 p. 7451 - 7455
反应条件
carbon in ethyl acetate 5 h; Heating;
参考文献
Pharmazie, , vol. 57, # 12 p. 791 - 795
