4,6-二氯-5-氨基嘧啶合成路线

参考文献

METHYLGENE, INC.
Patent: WO2006/10264 A1, 2006 ;
Location in patent: Page/Page column 195 ;
WO 2006/010264 A1

参考文献

Nemeryuk, M. P.; Sedov, A. L.; Krepelka, I.; Benes, Ya.; Safonova, T. S.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1983 , p. 1113 - 1115
Khimiya Geterotsiklicheskikh Soedinenii, 1983 , vol. 19, # 10 p. 1398 - 1400

5413-85-44,6-二氯-5-氨基嘧啶

88474-32-2(9ci)-5-氯-1H-1,2,3-噻唑-4-甲腈+

130623-77-7

参考文献

Nemeryuk, M. P.; Sedov, A. L.; Ryabokon, N. A.; Ershova, Yu. A.; Sokolova, A. S.; et al.
Pharmaceutical Chemistry Journal, 1990 , vol. 24, # 6 p. 406 - 410
Khimiko-Farmatsevticheskii Zhurnal, 1990 , vol. 24, # 6 p. 23 - 25

696-59-32,5-二甲氧基四氢呋喃+

5413-85-44,6-二氯-5-氨基嘧啶

934996-35-7

参考文献

Xiang, Jinbao; Zheng, Lianyou; Xie, Hongxiang; Hu, Xiaowei; Dang, Qun; Bai, Xu
Tetrahedron, 2008 , vol. 64, # 38 p. 9101 - 9107

5413-85-44,6-二氯-5-氨基嘧啶+

557-66-4乙胺盐酸盐

98140-03-56-氯-N4-乙基-4,5-嘧啶二胺

参考文献

MERCK SHARP and DOHME CORP.; ACHAB, Abdelghani Abe; ALTMAN, Michael D.; DENG, Yongqi; KATTAR, Solomon; KATZ, Jason D.; METHOT, Joey L.; ZHOU, Hua; MCGOWAN, Meredeth; CHRISTOPHER, Matthew P.; GARCIA, Yudith; ANTHONY, Neville John; FRADERA LLINAS, Francesc Xavier; YANG, Liping; MU, Changwei; WANG, Xiaona; SHI, Feng; YE, Baijun; ZHANG, Sixing; ZHAO, Xiaoli; ZHANG, Rong; FONG, Kin Chiu; LENG, Xiansheng
Patent: WO2014/75393 A1, 2014 ;
Location in patent: Page/Page column 62 ;

5413-85-44,6-二氯-5-氨基嘧啶+

75-04-7乙胺

98140-03-56-氯-N4-乙基-4,5-嘧啶二胺

参考文献

Lambertucci, Catia; Antonini, Ippolito; Buccioni, Michela; Dal Ben, Diego; Kachare, Dhuldeo D.; Volpini, Rosaria; Klotz, Karl-Norbert; Cristalli, Gloria
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 7 p. 2812 - 2822

5413-85-44,6-二氯-5-氨基嘧啶+

78-39-7原乙酸三乙酯+

132342-52-0

19186-33-5芒霉素

参考文献

Arita; Adachi; Ito; et al.
Journal of the American Chemical Society, 1983 , vol. 105, # 12 p. 4049 - 4055

5413-85-44,6-二氯-5-氨基嘧啶

454685-58-64,6-二碘-5-氨基嘧啶

参考文献

Latli, Bachir; Jones, Paul-James; Krishnamurthy, Dhileepkumar; Senanayake, Chris H.
Journal of Labelled Compounds and Radiopharmaceuticals, 2008 , vol. 51, # 1 p. 54 - 58

5413-85-44,6-二氯-5-氨基嘧啶

13190-82-4

参考文献

Csuk, Rene; Doerr, Petra
Tetrahedron, 1995 , vol. 51, # 20 p. 5789 - 5798

5413-85-44,6-二氯-5-氨基嘧啶

54660-92-35-氨基-1H-嘧啶-4,6-二硫酮

参考文献

ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2004/13141 A1, 2004 ;
Location in patent: Page 106-107 ;
WO 2004/013141 A1