2-(6-氯吡啶-3-基)乙胺合成路线 （共 4 条）
反应条件
1: With trifluoroacetic acid in dichloromethane
T=20°C;
2: With sodium hydroxide in water
pH=12;
参考文献
BAYER CROPSCIENCE SA
Patent: WO2006/8191 A1, 2006 ;
Location in patent: Page/Page column 25 ;
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran
T=0 - 20°C;
2: With water; sodium hydrogencarbonate in tetrahydrofuran
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
Patent: US2012/214785 A1, 2012 ;
Location in patent: Page/Page column 60 ;
反应条件
sodium borohydride in methanol; sodium hydroxide; dichloromethane
参考文献
Ciba-Geigy Corporation
Patent: US4115575 A1, 1978 ;
US 4115575 A
Title/Abstract Full Text Show Details
Ciba-Geigy Corporation
Patent: US4410530 A1, 1983 ;
反应条件
1.1: 1,1'-carbonyldiimidazole / tetrahydrofuran / 1 h / 45 °C
1.2: 20 °C
2.1: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C
View Scheme
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
Patent: US2012/214785 A1, 2012 ;
