2,3-二氯吡啶-5-羰酰氯合成路线

参考文献

SCHERING CORPORATION; PHARMACOPEIA DRUG DISCOVERY, INC.
Patent: WO2006/88840 A1, 2006 ;
Location in patent: Page/Page column 107-108 ;
WO 2006/088840 A1

54127-29-62,3-二氯吡啶-5-羰酰氯

54127-30-95,6-二氯-3-吡啶甲醇

参考文献

Graf
Journal fuer Praktische Chemie (Leipzig), 1932 , vol. <2>134, p. 177,184

54127-29-62,3-二氯吡啶-5-羰酰氯

75291-84-85,6-二氯烟酰胺

参考文献

Ognyanov, Vassil I.; Balan, Chenera; Bannon, Anthony W.; Bo, Yunxin; Dominguez, Celia; Fotsch, Christopher; Gore, Vijay K.; Klionsky, Lana; Ma, Vu V.; Qian, Yi-Xin; Tamir, Rami; Wang, Xianghong; Xi, Ning; Xu, Shimin; Zhu, Dawn; Gavva, Narender R.; Treanor, James J. S.; Norman, Mark H.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 12 p. 3719 - 3742

54127-29-62,3-二氯吡啶-5-羰酰氯

71690-05-65,6-二氯吡啶-3-甲醛

参考文献

Lahm, George P.; Cordova, Daniel; Barry, James D.; Pahutski, Thomas F.; Smith, Ben K.; Long, Jeffrey K.; Benner, Eric A.; Holyoke, Caleb W.; Joraski, Kathleen; Xu, Ming; Schroeder, Mark E.; Wagerle, Ty; Mahaffey, Michael J.; Smith, Rejane M.; Tong, My-Hahn
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 10 p. 3001 - 3006

54127-29-62,3-二氯吡啶-5-羰酰氯+

6638-79-5二甲羟胺盐酸盐

120800-05-72,3-二氯-5-乙酰基吡啶

参考文献

PURDUE PHARMA L.P.; SHIONOGI and CO., LTD.
Patent: WO2008/132600 A2, 2008 ;
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WO 2008/132600 A2

54127-29-62,3-二氯吡啶-5-羰酰氯

120800-05-72,3-二氯-5-乙酰基吡啶

参考文献

Kuo
Tetrahedron, 1992 , vol. 48, # 42 p. 9233 - 9236

54127-29-62,3-二氯吡啶-5-羰酰氯+

108-59-8丙二酸二甲酯

120800-05-72,3-二氯-5-乙酰基吡啶

参考文献

Kuo
Tetrahedron, 1992 , vol. 48, # 42 p. 9233 - 9236

41667-95-25,6-二氯烟酸

54127-29-62,3-二氯吡啶-5-羰酰氯

参考文献

PFIZER PRODUCTS INC.
Patent: WO2007/36769 A1, 2007 ;
Location in patent: Page/Page column 45 ;

54127-63-85-氯-6-羟基烟酸

54127-29-62,3-二氯吡啶-5-羰酰氯

参考文献

Ciba-Geigy Corporation
Patent: US4115575 A1, 1978 ;
US 4115575 A
Title/Abstract Full Text Show Details
Ciba-Geigy Corporation
Patent: US4410530 A1, 1983 ;

59-67-6烟酸+

7719-09-7氯化亚砜

85320-79-25-氯烟酰氯+

54127-29-62,3-二氯吡啶-5-羰酰氯

参考文献

Meyer,H.; Graf
Chemische Berichte, 1928 , vol. 61, # 2203 p. 2210
Full Text Show Details
Spaeth; Spitzer
Chemische Berichte, 1926 , vol. 59, p. 1479,1482
Full Text Show Details
Meyer,H.
Monatshefte fuer Chemie, 1901 , vol. 22, p. 116