2-氨基-4,6-二甲基吡啶合成路线 （共 43 条）
反应条件
hydrogenchloride in ethanol T=120°C; 0.333333 h; Microwave irradiation; Reagent/catalystTemperatureTime;
参考文献
Walia, Amit; Kang, Soosung; Silverman, Richard B
Journal of Organic Chemistry, 2013 , vol. 78, # 21 p. 10931 - 10937
反应条件
1: CH2Cl2 / Heating 2: conc. HCl View Scheme
参考文献
Bioorganic and medicinal chemistry letters, , vol. 10, # 17 p. 1975 - 1978
反应条件
methyl-magnesium chloride
参考文献
Tetrahedron Letters, , vol. 39, # 5-6 p. 383 - 384
反应条件
potassium hydroxide; sodium hypochlorite
参考文献
Yakugaku Zasshi, , vol. 62, p. 40; dtsch. Ref. S. 18
Chem.Abstr., , p. 620
反应条件
sodium amide; xylene
参考文献
Bulletin de la Societe Chimique de France, , p. 188,190
参考文献
Tetrahedron Letters, , vol. 39, # 5-6 p. 383 - 384
反应条件
1: Durchleiten von HCl 2: aqueous NH3 3: NaOCl; aqueous KOH View Scheme
参考文献
Yakugaku Zasshi, , vol. 62, p. 40; dtsch. Ref. S. 18
Chem.Abstr., , p. 620
反应条件
1: 59 percent / bromine; glacial acetic acid / 1.33 h / 20 °C 2: 64 percent / potassium nitrate; concd. sulfuric acid / 1 h / 20 °C 3: 98 percent / hydrogen; ammonium hydroxide / palladium on carbon / methanol / 18 h / 50 °C / 2585.74 Torr View Scheme
参考文献
Heitsch, Holger; Becker, Reinhard H.A.; Kleemann, Heinz-Werner; Wagner, Adalbert
Bioorganic and Medicinal Chemistry, 1997 , vol. 5, # 4 p. 673 - 678
反应条件
1: With hydrogen bromide; bromine; sodium nitrite T=-10 - 0°C; 0.5 h; 2: With sodium hydroxide in water T=10°C;
参考文献
Zhang, Feng; Zaidi, Saheem; Haney, Kendra M.; Kellogg, Glen E.; Zhang, Yan
Journal of Organic Chemistry, 2011 , vol. 76, # 19 p. 7945 - 7952
反应条件
1: With hydrogenchloride; sodium chloride; sodium nitrite in water T=-20 - 20°C; 2: With bicarbonate in water
参考文献
WO2009/130481 A1, ;
Page/Page column 126-127 ;
