3-(4-甲氧苯基)-1-丙醇合成路线 （共 74 条）
反应条件
lithium aluminium tetrahydride in diethyl ether 1.) 0 deg C, 0.5 h, 2.) 25 deg C, 5 h;
参考文献
Semmelhack, M.F.; Helquist, Paul; Jones, L.D.; Keller, Leonard; Mendelson L.; et al.
Journal of the American Chemical Society, 1981 , vol. 103, # 21 p. 6460 - 6471
反应条件
methanol; Na-SG in tetrahydrofuran T=0 - 25°C; Bouveault-Blanc reduction; Inert atmosphere;
参考文献
Bodnar, Brian S.; Vogt, Paul F.
Journal of Organic Chemistry, 2009 , vol. 74, # 6 p. 2598 - 2600
反应条件
potassium carbonate in acetone
参考文献
Gonzalez, Antonio G.; Silva, Margarita Hernandez; Padron, Juan I.; Leon, Francisco; Reyes, Eduardo; Alvarez-Mon, Melchor; Pivel, Juan P.; Quintana, Jose; Estevez, Francisco; Bermejo, Jaime
Journal of Medicinal Chemistry, 2002 , vol. 45, # 12 p. 2358 - 2361
反应条件
1: With hydrogen; palladium on activated charcoal in ethyl acetate T=20°C; 2: With lithium aluminium tetrahydride in tetrahydrofuran 5 h; Heating;
参考文献
Fronza, Giovanni; Fuganti, Claudio; Serra, Stefano; Cisero, Marco; Koziet, Joseph
Journal of agricultural and food chemistry, 2002 , vol. 50, # 10 p. 2748 - 2754
反应条件
samarium diiodide; water; triethylamine in tetrahydrofuran T=20°C; 2 h; Inert atmosphere;
参考文献
Szostak, Michal; Spain, Malcolm; Procter, David J.
Chemical Communications, 2011 , vol. 47, # 37 p. 10254 - 10256
反应条件
methanol; Na-SG in tetrahydrofuran T=0 - 25°C; Bouveault-Blanc reduction; Inert atmosphere;
参考文献
Bodnar, Brian S.; Vogt, Paul F.
Journal of Organic Chemistry, 2009 , vol. 74, # 6 p. 2598 - 2600
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 4 h; Heating;
参考文献
Duarte, Carolina De Mattos; Verli, Hugo; Araujo-Junior, Joao Xavier De; Medeiros, Isac Almeida De; Barreiro, Eliezer J.; Fraga, Carlos Alberto Manssour
European Journal of Pharmaceutical Sciences, 2004 , vol. 23, # 4-5 p. 363 - 369
反应条件
hydrogenchloride; water; 1-methyl-1-[4-(3-phenyl-propoxymethyl)-phenyl]-siletane in tetrahydrofuran 4 h;
参考文献
Tlais, Sami F.; Lain, Hubert; House, Sarah E.; Dudley, Gregory B.
Journal of Organic Chemistry, 2009 , vol. 74, # 5 p. 1876 - 1885
反应条件
1-methyl-1-[4-(3-phenyl-propoxymethyl)-phenyl]-siletane in tetrahydrofuran; water; acetic acid 4 h;
参考文献
Tlais, Sami F.; Lain, Hubert; House, Sarah E.; Dudley, Gregory B.
Journal of Organic Chemistry, 2009 , vol. 74, # 5 p. 1876 - 1885
反应条件
1.1: 76 percent / CH2Cl2 / 5 h / Heating 2.1: H2 / 10 percent Pd/C / ethyl acetate / 20 °C 2.2: 76 percent / LiAlH4 / tetrahydrofuran / 5 h / Heating View Scheme
参考文献
Journal of agricultural and food chemistry, , vol. 50, # 10 p. 2748 - 2754
