5-(3-氨基苯基)呋喃-2-羧酸甲酯合成路线 （共 4 条）
反应条件
hydrogen; palladium 10 on activated carbon in ethyl acetate P=1034.32 - 1551.49 Torr; 3 - 4 h; Product distribution / selectivity;
参考文献
SPIROGEN LIMITED
Patent: WO2005/85177 A2, 2005 ;
Location in patent: Page/Page column 52-54; 80 ;
反应条件
1: 51 percent / Pd(PPh3)4; aq. Na2CO3 / toluene; methanol / 6 h / Heating 2: 51 percent / H2 / Pd/C / methanol / 2 h / 20 °C / 2280 Torr View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 48, # 8 p. 2882 - 2891
反应条件
1: 51 percent / Pd(PPh3)4; aq. Na2CO3 / toluene; methanol / 6 h / Heating 2: 51 percent / H2 / Pd/C / methanol / 2 h / 20 °C / 2280 Torr View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 48, # 8 p. 2882 - 2891
反应条件
1: 87 percent / Cs2CO3 / dimethylformamide / 2.5 h / 0 - 20 °C 2: 85 percent / SnCl2*H2O / ethyl acetate / 3 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 50, # 13 p. 3101 - 3112
