4-氯-1H-吡唑并[3,4-d]嘧啶合成路线 (共 23 条)
反应条件
in N,N-dimethyl-formamide; toluene
T=0 - 25°C;
参考文献
TANABE SEIYAKU CO., LTD.
Patent: EP1772454 A1, 2007 ;
Location in patent: Page/Page column 61 ;
EP 1772454 A1
反应条件
1: thiourea; ethanol
2: aq. NaOH solution
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参考文献
Robins
Journal of the American Chemical Society, 1956 , vol. 78, p. 784,787
Journal of the American Chemical Society, 1957 , vol. 79, p. 6407,6413
参考文献
Seela, F.; Steker, H.
Tetrahedron Letters, 1984 , vol. 25, # 44 p. 5017 - 5018