4-氯-1H-吡唑并[3,4-d]嘧啶合成路线 （共 23 条）
参考文献
Robins
Journal of the American Chemical Society, 1956 , vol. 78, p. 784,787
Journal of the American Chemical Society, 1957 , vol. 79, p. 6407,6413
反应条件
caesium carbonate in N,N-dimethyl-formamide T=0°C; 3 h;
参考文献
US2007/281949 A1, ;
Page/Page column 37 ;
反应条件
1: With camphor-10-sulfonic acid in ethyl acetate
T=20°C; 70 h;
2: With sodium hydrogencarbonate in water; ethyl acetate
Saturated solution;
参考文献
Erickson, Shawn David; Gillespie, Paul; Guertin, Kevin Richard; Karnachi, Prabha Saba; Kim, Kyungjin; Ma, Chun; McComas, Warren William; Pietranico-Cole, Sherrie Lynn; Qi, Lida; Tilley, Jefferson Wright; Zhang, Qiang
Patent: US2009/286812 A1, 2009 ;
Location in patent: Page/Page column 28 ;
参考文献
Thompson, Wayne; Young, Steven D.; Phillips, Brian T.; Munson, Peter; Whitter, Willie; Liverton, Nigel; Dieckhaus, Christine; Butcher, John; McCauley, John A.; McIntyre, Charles J.; Layton, Mark E.; Sanderson, Philip E.
Patent: US2005/54658 A1, 2005 ;
Location in patent: Page/Page column 17 ;
US 20050054658 A1
反应条件
caesium carbonate in N,N-dimethyl-formamide
T=0°C; 3 h;
参考文献
Cephalon, Inc.
Patent: US2007/281949 A1, 2007 ;
Location in patent: Page/Page column 37 ;
参考文献
Koppel et al.
Journal of Organic Chemistry, 1959 , vol. 24, p. 259,260
参考文献
Robins
Journal of the American Chemical Society, 1956 , vol. 78, p. 784,787
Journal of the American Chemical Society, 1957 , vol. 79, p. 6407,6413
参考文献
Noell; Robins
Journal of Organic Chemistry, 1958 , vol. 23, p. 1547,1548
反应条件
caesium carbonate in N,N-dimethyl-formamide
T=0°C; 3 h;
参考文献
Zacharie, Boulos; Connolly, Timothy P.; Rej, Rabindra; Attardo, Giorgio; Penney, Christopher L.
Tetrahedron, 1996 , vol. 52, # 7 p. 2271 - 2278
参考文献
Robins
Journal of the American Chemical Society, 1956 , vol. 78, p. 784,787
Journal of the American Chemical Society, 1957 , vol. 79, p. 6407,6413
