六氢吡唑并[1,2-a]吡唑合成路线 （共 5 条）
反应条件
1: di-isobutylaluminium hydride
2: 74 percent / MgSO4 / CH2Cl2
3: 62 percent / LiAlH4 / 1,2-dimethoxy-ethane / 24 h / Ambient temperature
View Scheme
参考文献
Alder, Roger W.; Eastment, Paul; Moss, Richard E.; Sessions, Richard B.; Stringfellow, Martin A.
Tetrahedron Letters, 1982 , vol. 23, # 40 p. 4181 - 4184
反应条件
in acetonitrile
T=0°C; 4 h;
参考文献
Alder, Roger W.; Sessions, Richard B.; Bennet, Andrew J.; Moss, Richard E.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 603 - 610
反应条件
1: Raney nickel; H2O / Hydrogenation
View Scheme
参考文献
Stetter; Spangenberger
Chemische Berichte, 1958 , vol. 91, p. 1982,1987
反应条件
in chloroform; benzene
T=276.9°C; ΔG(excit); insitu ionization; Rate constantThermodynamic data;
参考文献
Nelsen, Stephen F.; Rumack, Daniel T.; Meot-Ner (Mautner), Michael
Journal of the American Chemical Society, 1987 , vol. 109, # 5 p. 1373 - 1379
反应条件
water; nickel
Hydrogenation;
参考文献
Alder, Roger W.; Eastment, Paul; Moss, Richard E.; Sessions, Richard B.; Stringfellow, Martin A.
Tetrahedron Letters, 1982 , vol. 23, # 40 p. 4181 - 4184
