acetic acid in ethanol
T=20°C; Cyclization; condensation; 110 h;
参考文献
Alberola, Angel; Calvo, Luis; Ortega, Alfonso Gonzalez; Sadaba, M. Luisa; Sanudo, M. Carmen; Granda, Santiago Garcia; Rodriguez, Elena Garcia
Heterocycles, 1999 , vol. 51, # 11 p. 2675 - 2686
hydrogenchloride in ethanol
T=20°C; Cyclization; condensation; 120 h; Title compound not separated from byproducts;
参考文献
Alberola, Angel; Calvo, Luis; Ortega, Alfonso Gonzalez; Sadaba, M. Luisa; Sanudo, M. Carmen; Granda, Santiago Garcia; Rodriguez, Elena Garcia
Heterocycles, 1999 , vol. 51, # 11 p. 2675 - 2686
acetic acid in ethanol
T=20°C; Cyclization; condensation; 110 h;
参考文献
Alberola, Angel; Calvo, Luis; Ortega, Alfonso Gonzalez; Sadaba, M. Luisa; Sanudo, M. Carmen; Granda, Santiago Garcia; Rodriguez, Elena Garcia
Heterocycles, 1999 , vol. 51, # 11 p. 2675 - 2686
triethylamine in benzene
T=30 - 50°C; 1.5 h; Yield given;
参考文献
Sheludyakov, V. D.; Sheludyakova, S. V.; Kuznetsova, M. G.; Silkina, N. N.; Mironov, V. F.
J. Gen. Chem. USSR (Engl. Transl.), 1980 , vol. 50, # 4 p. 875 - 881,705 - 711
1: H2SO4 / heating for few hours
2: -50 to -40 deg C, then r.t.
3: triethylamine / benzene / 1.5 h / 30 - 50 °C
View Scheme
参考文献
Sheludyakov, V. D.; Sheludyakova, S. V.; Kuznetsova, M. G.; Silkina, N. N.; Mironov, V. F.
J. Gen. Chem. USSR (Engl. Transl.), 1980 , vol. 50, # 4 p. 875 - 881,705 - 711
1: -50 to -40 deg C, then r.t.
2: triethylamine / benzene / 1.5 h / 30 - 50 °C
View Scheme
参考文献
Sheludyakov, V. D.; Sheludyakova, S. V.; Kuznetsova, M. G.; Silkina, N. N.; Mironov, V. F.
J. Gen. Chem. USSR (Engl. Transl.), 1980 , vol. 50, # 4 p. 875 - 881,705 - 711
