反应条件
1.1: sulfuric acid; nitric acid / 0.25 h / 0 °C
2.1: sodium hydride / N,N-dimethyl-formamide / 0.25 h / 20 °C / Inert atmosphere
2.2: 20 °C / Inert atmosphere
3.1: 10 palladium on activated carbon; hydrazine hydrate / ethanol / 60 °C
View Scheme
参考文献
Weinberg, Linda R.; Albom, Mark S.; Angeles, Thelma S.; Husten, Jean; Lisko, Joseph G.; McHugh, Robert J.; Milkiewicz, Karen L.; Murthy, Seetha; Ott, Gregory R.; Theroff, Jay P.; Tripathy, Rabindranath; Underiner, Ted L.; Zificsak, Craig A.; Dorsey, Bruce D.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 1 p. 164 - 167