2-甲基-4-(5-硝基-2-呋喃基)噻唑合成路线 （共 7 条）
反应条件
sulfuric acid; nitric acid in acetic acid
T=0 - 5°C; 0.5 h;
参考文献
Saldabol; Popelis; Slavinska
Chemistry of Heterocyclic Compounds, 2002 , vol. 38, # 7 p. 873 - 881
反应条件
in ethanol
3 h; Heating;
参考文献
Khadse, B. G.; Lokhande, S. R.; Bhamaria, R. P.; Prabhu, S. R.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, # 1-12 p. 856 - 860
反应条件
sodium nitrite in acetic acid
参考文献
Saldabol,N.O. et al.
Zhurnal Organicheskoi Khimii, 1979 , vol. 15, p. 2547 - 2554,2303 - 2310
反应条件
1: 72 percent / thionyl chloride / benzene / 2 h / Heating
2: 2) HCl gas / 1) ether, overnight
3: 62 percent / ethanol / 3 h / Heating
View Scheme
参考文献
Khadse, B. G.; Lokhande, S. R.; Bhamaria, R. P.; Prabhu, S. R.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, # 1-12 p. 856 - 860
反应条件
1: 2) HCl gas / 1) ether, overnight
2: 62 percent / ethanol / 3 h / Heating
View Scheme
参考文献
Khadse, B. G.; Lokhande, S. R.; Bhamaria, R. P.; Prabhu, S. R.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, # 1-12 p. 856 - 860
反应条件
1: ethanol
2: NaNO2 / acetic acid
View Scheme
参考文献
Saldabol,N.O. et al.
Zhurnal Organicheskoi Khimii, 1979 , vol. 15, p. 2547 - 2554,2303 - 2310
参考文献
Sherman,W.R.; Dickson,D.E.
Journal of Organic Chemistry, 1962 , vol. 27, p. 1351 - 1355
