2-氨基对苯二甲酸二甲酯合成路线 （共 39 条）
反应条件
1.1: sulfuric acid; aq. sodium nitrite / 0.5 h / 0 °C
1.2: 66.5 percent / aq. sulfuric acid / 0.33 h / 120 °C
2.1: 63 percent / sulfuric acid / 48 h / 80 °C
View Scheme
参考文献
Bolton, Onas; Kim, Jinsang
Journal of Materials Chemistry, 2007 , vol. 17, # 19 p. 1981 - 1988
反应条件
1: 60 percent / pyridine / 24 h / Ambient temperature
2: 1.) sodium hydride / 1.0 DMF, 2.) DMF, 16 h
3: 90 percent / aq. methanolic sodium hydroxide / 3 h / Heating
4: thionyl chloride
5: aluminum chloride / CH2Cl2 / 0.5 h / 0 °C
6: CH2Cl2; diethyl ether / 0.5 h
7: silver benzoate / 0.08 h / Heating
8: 71 percent / conc. hydrochloric acid / acetic acid / 4 h / Heating
View Scheme
参考文献
Dunn, James P.; Muchowski, Joseph M.; Nelson, Peter N.
Journal of Medicinal Chemistry, 1981 , vol. 24, # 9 p. 1097 - 1099
反应条件
methanol; potassium hydroxide
参考文献
Cahn-Speyer
Monatshefte fuer Chemie, 1907 , vol. 28, p. 816
参考文献
Cahn-Speyer
Monatshefte fuer Chemie, 1907 , vol. 28, p. 816
反应条件
acetic acid in water
T=60 - 75°C; 23 h;
参考文献
PFIZER PRODUCTS INC.
Patent: WO2007/125405 A2, 2007 ;
Location in patent: Page/Page column 20; 48-49; 52 ;
WO 2007/125405 A2
反应条件
1.1: hydrogenchloride; sodium nitrite / water / 1.25 h / 0 - 5 °C
1.2: 18 h / 20 °C
2.1: diisobutylaluminium hydride / tetrahydrofuran; hexanes; hexane / 6 h / -78 °C
3.1: pyridinium chlorochromate / dichloromethane / 24 h / 20 °C
View Scheme
参考文献
Wu, Yubo; Guo, Huimin; Zhang, Xin; James, Tony D.; Zhao, Jianzhang
Chemistry - A European Journal, 2011 , vol. 17, # 27 p. 7632 - 7644
参考文献
Deshmukh, Mininath S.; Sekar, Nagaiyan
Dyes and Pigments, 2014 , vol. 103, p. 25 - 33
参考文献
Cahn-Speyer
Monatshefte fuer Chemie, 1907 , vol. 28, p. 816
Full Text Show Details
Wegscheider; Faltis; Black; Huppert
Monatshefte fuer Chemie, 1912 , vol. 33, p. 152,156, 166
参考文献
Wegscheider; Faltis; Black; Huppert
Monatshefte fuer Chemie, 1912 , vol. 33, p. 152,156, 166
