N-[2-[3-(2-氰基苯氧基)-2-羟基丙基氨基]乙基]-N'-苯基脲合成路线 （共 4 条）
反应条件
sodium hydroxide in propan-1-ol; water
T=90°C; 0.5 h;
参考文献
Kopka, Klaus; Wagner, Stefan; Riemann, Burkhard; Law, Marilyn P; Puke, Carsten; Luthra, Sajinder K; Pike, Victor W; Wichter, Thomas; Schmitz, Wilhelm; Schober, Otmar; Schaefers, Michael
Bioorganic and medicinal chemistry, 2003 , vol. 11, # 16 p. 3513 - 3527
反应条件
sodium hydroxide in propan-1-ol
18 h; Heating;
参考文献
Large, M.S.; Smith, L.H.
Journal of Medicinal Chemistry, 1982 , vol. 25, # 11 p. 1286 - 1292
反应条件
1: 71 percent / NaOH / H2O / 50 °C
2: 41 percent / NaOH / propan-1-ol; H2O / 0.5 h / 90 °C
View Scheme
参考文献
Kopka, Klaus; Wagner, Stefan; Riemann, Burkhard; Law, Marilyn P; Puke, Carsten; Luthra, Sajinder K; Pike, Victor W; Wichter, Thomas; Schmitz, Wilhelm; Schober, Otmar; Schaefers, Michael
Bioorganic and medicinal chemistry, 2003 , vol. 11, # 16 p. 3513 - 3527
反应条件
1: HCl / methanol; H2O / 2.5 h / 45 - 50 °C / 39.75 - 74.26 Torr
2: 41 percent / NaOH / propan-1-ol; H2O / 0.5 h / 90 °C
View Scheme
参考文献
Kopka, Klaus; Wagner, Stefan; Riemann, Burkhard; Law, Marilyn P; Puke, Carsten; Luthra, Sajinder K; Pike, Victor W; Wichter, Thomas; Schmitz, Wilhelm; Schober, Otmar; Schaefers, Michael
Bioorganic and medicinal chemistry, 2003 , vol. 11, # 16 p. 3513 - 3527
