反应条件
1: 80 percent / tetrabutylammonium bromide, aq. NaOH / CH2Cl2
2: 1.) NaH / 1.) ether, -5-0 deg C, 10 min, 2.) ether, 10-15 deg C, 3 h
3: 1.) conc. HCl, 2.) PTS-acid / 1.) CH2Cl2-ether, 1 h, 2.) CH2Cl2, 0 deg C, 3 h
4: 1.) base, 2.) Jones reagent
View Scheme
参考文献
Rao, A.V. Rama; Deshpande, V.H.; Reddy, S. Pulla
Synthetic Communications, 1984 , vol. 14, # 5 p. 469 - 476
