1: 71 percent / diisopropylamine; Bu-Li / tetrahydrofuran; hexane / -78 - 20 °C 2: 78 percent / O3 / methanol / 48 h / 20 °C 3: 95 percent / Alkaline hydrolysis View Scheme

1: 71 percent / diisopropylamine; Bu-Li / tetrahydrofuran; hexane / -78 - 20 °C 2: 78 percent / O3 / methanol / 48 h / 20 °C 3: 95 percent / Alkaline hydrolysis View Scheme