5-氨基-1,3-二苯基哌唑合成路线 （共 30 条）
反应条件
in tetrahydrofuran
Inert atmosphere;
参考文献
Su, Wei-Nien; Lin, Tsung-Ping; Cheng, Kaung-Min; Sung, Kuan-Chin; Lin, Shao-Kai; Wong, Fung Fuh
Journal of Heterocyclic Chemistry, 2010 , vol. 47, # 4 p. 831 - 837
反应条件
phosphorus tribromide
T=50 - 60°C; Inert atmosphere;
参考文献
Chang, Chun-Hsi; Tsai, Henry J.; Huang, Yu-Ying; Lin, Hui-Yi; Wang, Li-Ya; Wu, Tian-Shung; Wong, Fung Fuh
Tetrahedron, 2013 , vol. 69, # 4 p. 1378 - 1386
反应条件
1: 81 percent / Ambient temperature
2: POCl3 / 3 h
3: 95 percent / (NH4)2CO3 / acetic acid / 3 h / Heating
View Scheme
参考文献
Simay, A.; Takacs, K.; Horvath, K.; Dvortsak, P.
Acta Chimica Academiae Scientiarum Hungaricae, 1980 , vol. 105, p. 127 - 140
反应条件
1: 4-nitrobenzaldehdye; N-acetyl-glycine With sodium acetate; acetic anhydride
Heating;
2: 1,3-Diphenyl-5-amino pyrazole Heating;
参考文献
Zonouzi, Afsaneh; Mirzazadeh, Roghieh; Talebi, Marzieh; Jafarypoor, Razieh; Peivandi, Azadeh; Ng, Seik Weng
Heterocycles, 2010 , vol. 81, # 9 p. 2131 - 2138
反应条件
1: 95 percent / acetone / 3 h / Heating
2: 40 percent / 5 h
View Scheme
参考文献
Fahmy; Ibraheim; Abouhadid; et al.
Archiv der Pharmazie, 1982 , vol. 315, # 9 p. 791 - 797
反应条件
zinc(II) chloride in hydrogenchloride; ethanol
1 h; Heating;
参考文献
Lynch; Khan; Teo; Pedrotti
Canadian Journal of Chemistry, 1988 , vol. 66, # 3 p. 420-428
反应条件
hydrogenchloride; sodium nitrite in water
T=0 - 20°C;
参考文献
Rizk, Hala F.; Ei-Badawi, Mahmoud A.; Ibrahim, Seham A.; Ei-Borai, Mohamed A.
Chinese Journal of Chemistry, 2011 , vol. 29, # 7 p. 1451 - 1459
反应条件
acetic acid; sodium nitrite
参考文献
Cusmano
Gazzetta Chimica Italiana, 1939 , vol. 69, p. 594,600,601
反应条件
1: benzaldehyde; N-acetyl-glycine With sodium acetate; acetic anhydride
Heating;
2: 1,3-Diphenyl-5-amino pyrazole Heating;
参考文献
Zonouzi, Afsaneh; Mirzazadeh, Roghieh; Talebi, Marzieh; Jafarypoor, Razieh; Peivandi, Azadeh; Ng, Seik Weng
Heterocycles, 2010 , vol. 81, # 9 p. 2131 - 2138
反应条件
1: N-(benzoyl)glycine; 4-methoxy-benzaldehyde With sodium acetate; acetic anhydride
Heating;
2: 1,3-Diphenyl-5-amino pyrazole Heating;
参考文献
Zonouzi, Afsaneh; Mirzazadeh, Roghieh; Talebi, Marzieh; Jafarypoor, Razieh; Peivandi, Azadeh; Ng, Seik Weng
Heterocycles, 2010 , vol. 81, # 9 p. 2131 - 2138
