3-羟基-4-苯基-2-丁酮合成路线 （共 14 条）
反应条件
formic acid; triethylamine; palladium diacetate in tetrahydrofuran
Heating;
参考文献
Torii, Sigeru; Okumoto, Hiroshi; Nakayasu, Seizo; Kotani, Takayuki
Chemistry Letters, 1989 , p. 1975 - 1978
反应条件
formic acid; triethylamine; Pd0-EnCatTM in ethyl acetate
T=23°C; 6 h; Title compound not separated from byproducts;
参考文献
Ley, Steven V.; Mitchell, Claire; Pears, David; Ramarao, Chandrashekar; Yu, Jin-Quan; Zhou, Wuzong
Organic Letters, 2003 , vol. 5, # 24 p. 4665 - 4668
反应条件
1: 54 percent / hydrogen peroxide; NaOH / methanol; H2O / 3.5 h / 5 - 20 °C
2: formic acid; triethylamine / Pd0-EnCatTM / ethyl acetate / 6 h / 23 °C
View Scheme
参考文献
Ley, Steven V.; Mitchell, Claire; Pears, David; Ramarao, Chandrashekar; Yu, Jin-Quan; Zhou, Wuzong
Organic Letters, 2003 , vol. 5, # 24 p. 4665 - 4668
反应条件
hydrogenchloride in water
参考文献
Ohba; Wakayama; Ikeda; Takei
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 10 p. 1127 - 1132
反应条件
ketoacid decarboxylase in phosphate buffer; dimethyl sulfoxide
T=30°C; pH=6.8; Title compound not separated from byproducts.;
参考文献
Gocke, Doerte; Nguyen, Cong Luan; Pohl, Martina; Stillger, Thomas; Walter, Lydia; Mueller, Michael
Advanced Synthesis and Catalysis, 2007 , vol. 349, # 8-9 p. 1425 - 1435
反应条件
silver hexafluoroantimonate; {1,3-bis[2,6-di(propan-2-yl)phenyl]-1,3-dihydro-2H-imidazol-2-ylidene}AuCl; water in methanol
T=60°C;
参考文献
Ramon, Ruben S.; Marion, Nicolas; Nolan, Steven P.
Tetrahedron, 2009 , vol. 65, # 9 p. 1767 - 1773
反应条件
potassium carbonate in methanol
0.166667 h;
参考文献
Scheid, Guenther; Kuit, Wouter; Ruijter, Eelco; Orru, Romano V. A.; Henke, Erik; Bornscheuer, Uwe; Wessjohann, Ludger A.
European Journal of Organic Chemistry, 2004 , # 5 p. 1063 - 1074
反应条件
potassium carbonate in methanol
0.166667 h;
参考文献
Scheid, Guenther; Kuit, Wouter; Ruijter, Eelco; Orru, Romano V. A.; Henke, Erik; Bornscheuer, Uwe; Wessjohann, Ludger A.
European Journal of Organic Chemistry, 2004 , # 5 p. 1063 - 1074
反应条件
1: 46 percent / LiCl; H2O / dimethylformamide / 5 h / 160 °C
2: aq. K2CO3 / methanol / 0.17 h
View Scheme
参考文献
Scheid, Guenther; Kuit, Wouter; Ruijter, Eelco; Orru, Romano V. A.; Henke, Erik; Bornscheuer, Uwe; Wessjohann, Ludger A.
European Journal of Organic Chemistry, 2004 , # 5 p. 1063 - 1074
反应条件
1: 67 percent / p-TsOH*H2O / benzene / 78 °C
2: aq. K2CO3 / methanol / 0.17 h
View Scheme
参考文献
Scheid, Guenther; Kuit, Wouter; Ruijter, Eelco; Orru, Romano V. A.; Henke, Erik; Bornscheuer, Uwe; Wessjohann, Ludger A.
European Journal of Organic Chemistry, 2004 , # 5 p. 1063 - 1074
