1-甲基-3-氧代-2-哌嗪乙酸甲酯合成路线 (共 3 条)
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran 2 h; Heating / reflux; 2: With sodium hydroxide; water in tetrahydrofuran pH=12;
参考文献
SAREUM LIMITED
Patent: WO2008/139161 A1, 2008 ;
Location in patent: Page/Page column 220-221 ;
WO 2008/139161 A1
反应条件
in methanol
T=25°C; 24 h; Title compound not separated from byproducts;
参考文献
Abelman, Matthew M.; Fisher, Karl J.; Doerffler, Edward M.; Edwards, Paul J.
Tetrahedron Letters, 2003 , vol. 44, # 9 p. 1823 - 1826
反应条件
in methanol
T=25°C; 24 h; Title compound not separated from byproducts;
参考文献
Abelman, Matthew M.; Fisher, Karl J.; Doerffler, Edward M.; Edwards, Paul J.
Tetrahedron Letters, 2003 , vol. 44, # 9 p. 1823 - 1826