3,5-二甲基-4-硝基苯酚合成路线 （共 21 条）
参考文献
Eiden; Leister; Mayer
Arzneimittel-Forschung/Drug Research, 1983 , vol. 33, # 1 p. 101 - 105
反应条件
1: 87.5 percent / 25percent KOH / 48 h / 60 °C
2: 38.2 percent / 1 h / 230 °C
View Scheme
参考文献
Eiden; Leister; Mayer
Arzneimittel-Forschung/Drug Research, 1983 , vol. 33, # 1 p. 101 - 105
参考文献
Adams; Stewart
Journal of the American Chemical Society, 1941 , vol. 63, p. 2859,2861
参考文献
v. Auwers; Borsche
Chemische Berichte, 1915 , vol. 48, p. 1713
反应条件
Reaktion ueber mehrere Stufen;
参考文献
Rowe et al.
Journal of the Society of Chemical Industry, London, 1930 , vol. 49, p. 469 T, 472 T
反应条件
1: 1.) NaBH4, 2.) 3 N HCl / 1.) 10percent Pd-C / 1.) H2O, MeOH, rt, 30 min
2: aq. NaNO2, aq. H2SO4 / 0.33 h / 20 °C
View Scheme
参考文献
Bucher, Goetz; Sander, Wolfram
Journal of Organic Chemistry, 1992 , vol. 57, # 5 p. 1346 - 1351
反应条件
nitric acid; acetic acid
T=70°C;
参考文献
Rowe et al.
Journal of the Society of Chemical Industry, London, 1930 , vol. 49, p. 469 T, 472 T
参考文献
Rowe et al.
Journal of the Society of Chemical Industry, London, 1930 , vol. 49, p. 469 T, 472 T
反应条件
in ethyl acetate; acetone
参考文献
William H. Rorer, Inc.
Patent: US4564640 A1, 1986 ;
参考文献
Rowe et al.
Journal of the Society of Chemical Industry, London, 1930 , vol. 49, p. 469 T, 472 T
